3′-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-5-fluorospiro[3H-indole-3,2′-thiazolidine]-2(1H),4′-dione

被引:11
|
作者
Jain, SC [1 ]
Sinha, J
Bhagat, S
Babu, BR
Bali, S
Errington, W
机构
[1] Univ Delhi, Dept Chem, Delhi 110007, India
[2] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England
关键词
D O I
10.1107/S010827019900966X
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis and structure of the title compound, C21H17FN4O3S, is described. It is a novel spiro-indole in which the sp(3) spiro-C atom is linked to S and N atoms. The pyrazole ring is aligned at 76.8(1)degrees with respect to the attached phenyl ring and at 87.7(1)degrees with respect to the best plane through the spiro ring. Molecules are linked to form infinite chains by N-H ... O hydrogen bonds, with N ... O = 2.7002(15) Angstrom.
引用
收藏
页码:1826 / 1829
页数:4
相关论文
共 50 条
  • [41] 1-Acetyl-2-oxo-4′-methyl-2a′-phenylspiro[3H-indole3,2′(2a′H,5a′H)-oxeto[3,2-d]oxazole]
    Usman, A
    Razak, IA
    Fun, HK
    Chantrapromma, S
    Zhang, Y
    Xu, JH
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2002, 58 : o145 - o147
  • [42] (E)-5-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)iminomethyl]-2-methoxyphenyl 4-bromobenzenesulfonate
    Guo, Min-Jie
    Chen, Xin
    Yao, Jing-Xia
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1360 - U1006
  • [43] Preparation and Reactions of 2-Methyl-7-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-5-arylthiazolo[3,2-a]-pyrimido[4,5-d]oxazin-4(5H)-one
    Youssef, Mohamed Salah K.
    Abbady, Mohamed S.
    Ahmed, Ragaa A.
    Omar, Ahmed A.
    CHINESE JOURNAL OF CHEMISTRY, 2011, 29 (07) : 1473 - 1482
  • [44] 3′-(3-Hydroxyphenyl)-4-methylspiro[benzo[e][1,4] diazepine-3,2′-oxirane]-2,5(1H, 4H)-dione
    Liu, Jun-Liang
    Hu, Zhi-Yu
    Xu, Qing-Yan
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1670 - U532
  • [45] 1′-methyl-4′-tolyl-1H-indole-3-spiro-2′-pyrrolidine-3′-spiro-5"-(thiazolo[3,2-b][1,2,4]triazole)-2,6"(3H,5"H)-dione
    Li, XF
    Feng, YQ
    Gao, B
    Yao, GY
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O1796 - O1797
  • [46] Microwave-Assisted, Solvent-Free Synthesis of 3′-(Aryl/Heteroaryl)-1-morpholinomethyl/piperidinomethylspiro[3H-indole-3,2′-thiazolidine]-2,4′(1H)-diones via 3-Isatinimines
    Pandey, Manju
    Raghuvanshi, Dushyant Singh
    Singh, Krishna Nand
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2009, 46 (01) : 49 - 53
  • [47] 1,1′,3,3′,5,5′-Hexamethylspiro[furo[2,3-d]pyrimidine-6(5H),5′-pyrimidine]-2,2′,4,4′,6′(1H,3H,1′H,3′H,5′H)-pentaone
    Pesyan, Nader Noroozi
    Rastgar, Saeed
    Hosseini, Yaser
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O1444 - U3327
  • [48] 4-[(3-Hydroxy-5-phenyl-1H-pyrazol-4-yl)-methyl]-5-phenyl-1H-pyrazol-3(2H)-one
    Baryala, Yamna
    Zerzouf, Abdelfettah
    Essassi, El Mokhtar
    Reuter, Hans
    Eickmeier, Henning
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2554 - O2556
  • [49] Bridgehead nitrogen spiroheterocyclic systems :: Synthesis and antimicrobial activity of spiro-[3H-5-bromoindole-3,2′-thiazolidine]-2[1H], 4′-(5′H)-diones and cis-3′,3a-dihydrospiro [3H, 5-bromoindole-3,5′-pyrazolo [3′,4′:4,5]-thiazol-2-(1H)-ones
    Mohan, Late Jag
    Rathee, Anju
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 17 (04) : 327 - 330
  • [50] 5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide
    Celikesir, Sevim Turktekin
    Akkurt, Mehmet
    Ustundag, Gokce Cihan
    Buyukgungor, Orhan
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1229 - +