3′-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-5-fluorospiro[3H-indole-3,2′-thiazolidine]-2(1H),4′-dione

被引：11

作者：

Jain, SC ^{[1
]}

Sinha, J

Bhagat, S

Babu, BR

Bali, S

Errington, W

机构：

[1] Univ Delhi, Dept Chem, Delhi 110007, India

[2] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1999年 / 55卷

关键词：

D O I：

10.1107/S010827019900966X

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and structure of the title compound, C21H17FN4O3S, is described. It is a novel spiro-indole in which the sp(3) spiro-C atom is linked to S and N atoms. The pyrazole ring is aligned at 76.8(1)degrees with respect to the attached phenyl ring and at 87.7(1)degrees with respect to the best plane through the spiro ring. Molecules are linked to form infinite chains by N-H ... O hydrogen bonds, with N ... O = 2.7002(15) Angstrom.

引用

页码：1826 / 1829

页数：4

共 50 条

[1] Synthesis of some novel isoxazolyl-spiro-[3H-indole-3,2′-thiazolidine]-2,4′-(1H)-diones, [3H-indole-3,4′-azetidine]-2,2′-(1H)-diones and [3H-indole-3,5′-3′-phenyl-1′,2′,4′-oxadiazoline]-2(1H)-ones
Rajanarendar, E.
Mohan, G.
Ramesh, P.
Rao, E. Kalyan
HETEROCYCLIC COMMUNICATIONS, 2006, 12 (06) : 431 - 436
[2] POTENTIAL ANTICONVULSANTS .7. SYNTHESIS OF 5'-METHYLSPIRO[3H-INDOLE-3,2'-THIAZOLIDINE]-2,4'(1H)-DIONES
RAJOPADHYE, M
POPP, FD
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (02) : 289 - 291
[3] A CONVENIENT SYNTHESIS AND REACTIONS OF SPIRO [3H-INDOLE-3,2'-THIAZOLIDINE]-2,4'(1H)-DIONES
JOSHI, KC
PATNI, R
CHAND, P
HETEROCYCLES, 1981, 16 (09) : 1555 - 1559
[4] ON ANTIMICROBIAL ACTIVITY OF 3'-PHENYLSPIRO[3H-INDOLE-3, 2'-THIAZOLIDINE]-2,4' (1H)-DIONES
DIURNO, MV
MAZZONI, O
PISCOPO, E
BOLOGNESE, A
FARMACO, 1993, 48 (03): : 435 - 441
[5] 1-Acetyl-3′-(4-bromophenyl)-3′-chlorospiro[3H-indole-3,2′-oxetan]-2(1H)-one
Usman, A
Razak, IA
Fun, HK
Chantrapromma, S
Zhang, Y
Xu, JH
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2002, 58 (05): : o287 - o288
[6] Synthesis and QSAR study of novel cytotoxic spiro[3H-indole-3,2′(1′H)-pyrrolo[3,4-c]pyrrole]-2,3′,5′(1H,2′aH,4′H)-triones
Girgis, Adel S.
Stawinski, Jacek
Ismail, Nasser S. M.
Farag, Hanaa
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 47 : 312 - 322
[7] REACTION OF SCHIFF-BASES WITH MERCAPTO ACIDS SYNTHESIS OF SPIRO[2H-1,3-BENZOTHIAZINE-2,3'-[3H]INDOLE]-2',4(1'H,3H)-DIONES AND SPIRO[3H-INDOLE-3,2'-THIAZOLIDINE]-2,4'(1H)-DIONES
JAIN, R
VAJPEI, S
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1992, 70 (1-2): : 63 - 66
[8] Condensed bridgehead nitrogen spiroheterocyclic systems:: Spiro [3H-5-bromo indole-3,2′-thiazolidine]-2-(1H, 4′(5′H)-dione and cis-3′,3′ a-dihydrospiro-[3H-5-bromoindole-3,5′-pyrazolo [3′,4′:4,5] thiazolo-2-(1H)-ones]
Mohan, J
Kumar, A
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 14 (02) : 173 - 174
[9] 3-Methyl-1-(pyridin-2-yl)-4-(1-pyridin-2-yl-3-methyl-1H-pyrazol-5-yl)-2H-3-pyrazolin-5(1H)-one
Djerrari, B
Essassi, EM
Fifani, J
Pierrot, M
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2001, 57 : O1126 - O1127
[10] FACILE SYNTHESIS OF SPIRO[3H-INDOLE-3,2 '-OXIRANE]-3 '-(2-OXO-2-(THIOPHENE-2-YL))-2(1H)ONES AND THEIR ANTIBACTERIAL ACTIVITY
Sharma, Kanti
Sharma, Lokesh Kumar
Jain, Renuka
HETEROCYCLIC LETTERS, 2015, 5 (03): : 383 - 390

← 1 2 3 4 5 →