T cell Ig and mucin 1 (TIM-1) is expressed on in vivo- activated T cells and provides a costimulatory signal for T cell activation.

被引：0
|
作者：
de Souza, Anjah J. [1 ]
Oriss, Timothy B. [1 ]
O'Malley, Katherine J. [1 ]
Ray, Anuradha [1 ]
Kane, Lawrence P. [1 ]
机构：
[1] Univ Pittsburgh, Sch Med, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA 15261 USA
来源：
JOURNAL OF IMMUNOLOGY | 2006年 / 176卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：S186 / S186
页数：1
相关论文
共 50 条
  • [21] Tim-1 Signaling Substitutes for Conventional Signal 1 and Requires Costimulation to Induce T Cell Proliferation
    Mariat, Christophe
    Degauque, Nicolas
    Balasubramanian, Savithri
    Kenny, James
    DeKruyff, Rosemarie H.
    Umetsu, Dale T.
    Kuchroo, Vijay
    Zheng, Xin Xiao
    Strom, Terry B.
    JOURNAL OF IMMUNOLOGY, 2009, 182 (03): : 1379 - 1385
  • [22] Tim-4 is the ligand for Tim-1, and the Tim-1/Tim-4 interaction regulates T cell expansion.
    Meyers, JH
    Chakravarti, S
    Schlesinger, D
    Illes, Z
    Waldner, H
    Umetsu, SE
    Kenny, J
    Zheng, XX
    Umetsu, DT
    DeKruyff, RH
    Strom, TB
    Kuchroo, VK
    CLINICAL IMMUNOLOGY, 2005, 115 : S35 - S36
  • [23] T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
    Kondratowicz, Andrew S.
    Lennemann, Nicholas J.
    Sinn, Patrick L.
    Davey, Robert A.
    Hunt, Catherine L.
    Moller-Tank, Sven
    Meyerholz, David K.
    Rennert, Paul
    Mullins, Robert F.
    Brindley, Melinda
    Sandersfeld, Lindsay M.
    Quinn, Kathrina
    Weller, Melodie
    McCray, Paul B., Jr.
    Chiorini, John
    Maury, Wendy
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (20) : 8426 - 8431
  • [24] Inverse association between T cell immunoglobulin and mucin domain-1 (TIM-1) and T-bet in a mouse model of allergic rhinitis
    Xu, G.
    Li, H.
    ALLERGY, 2007, 62 : 101 - 101
  • [25] Tim-4 Ig Inhibits CD4+ T Cell Responses by a Tim-1 Independent Pathway In Vitro
    Cao, Wei
    Ryan, Michelle
    O'Connor, Rosemary
    Clarkson, Michael
    AMERICAN JOURNAL OF TRANSPLANTATION, 2010, 10 : 364 - 364
  • [26] THE LFA-1 LIGAND ICAM-1 PROVIDES AN IMPORTANT COSTIMULATORY SIGNAL FOR T-CELL RECEPTOR-MEDIATED ACTIVATION OF RESTING T-CELLS
    VANSEVENTER, GA
    SHIMIZU, Y
    HORGAN, KJ
    SHAW, S
    JOURNAL OF IMMUNOLOGY, 1990, 144 (12): : 4579 - 4586
  • [27] Activation of the tim-1 pathway disarms regulatory T cells networks.
    Vu, Minh Diem
    Gao, Wenda
    Degauque, Nicolas
    Zhang, Dong
    Li, Man Chang
    AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 : 228 - 228
  • [28] T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase
    de Souza, Anjali J.
    Oak, Jean S.
    Jordanhazy, Ryan
    DeKruyff, Rosemarie H.
    Fruman, David A.
    Kane, Lawrence P.
    JOURNAL OF IMMUNOLOGY, 2008, 180 (10): : 6518 - 6526
  • [29] TIM1 modulation of T cell activation
    Binne, Lauri
    Scott, Martin
    Rennert, Paul
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S201 - S201
  • [30] Neural stem cell express costimulatory molecules and induce T cell activation.
    Imitola, J
    Comabella, M
    Snyder, EY
    Sayegh, MH
    Khoury, SJ
    CLINICAL IMMUNOLOGY, 2002, 103 (03) : S63 - S63
12345