The purpose of this research is to develop the usage intention model of online e-learning systems. Based on the Technology Acceptance Model and D&M model, the proposed framework is validated with 285 respondents from online e-learning users in Taiwan, which shows that information quality, service quality, perceived ease of use and perceived usefulness are play an critical role to determine user satisfaction of e-learning system. More importantly, the perception of user satisfaction is key aspect affecting intention to use of e-learning system. According to the statistical results, an acceptable goodness-of-fit indicates that proposed model and samples is proper to exam the hypotheses. This study emphasizes that the managers and designers of e-learning system provider should pay more attention to understanding the perceptions of users' satisfaction and improving the service and information quality of the system. Therefore, successful e-learning systems not only provide robust service quality of information systems, but also delivery reliable information quality of online e-learning platform.