BMP-2 gene polymorphisms and osteoporosis:: The Rotterdam Study

被引：32
|
作者：
Medici, Marco
van Meurs, Joyce B. J.
Rivadeneira, Fernando
Zhao, HongYan
Arp, Pascal P.
Hofman, Albert
Pols, Huibert A. P.
Uitterlinden, Andre G. [1 ]
机构：
[1] Erasmus Univ, Med Ctr, Dept Internal Med, Rotterdam, Netherlands
[2] Erasmus Univ, Med Ctr, Dept Epidemiol & Biostat, Rotterdam, Netherlands
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2006年 / 21卷 / 06期
关键词：
genetic; polymorphism; association; haplotypes; fractures;
D O I：
10.1359/JBMR.060306
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
After reported associations of variations in the BMP-2 gene with osteoporosis in small populations, we studied the association of the BMP-2 gene polymorphisms Ser37Ala and Arg190Ser with osteoporosis in 6353 men and women from the Rotterdam Study. We did not observe an association of these variants with BMD, bone loss, hip structural analysis parameters, and fracture risk.
引用
收藏
页码：845 / 854
页数：10
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