WT RAS signaling is an essential therapeutic target in RAS mutated cancers

被引:0
|
作者
Sealover, Nancy E. [1 ]
Kortum, Robert L. [1 ]
机构
[1] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
413
引用
下载
收藏
页数:1
相关论文
共 50 条
  • [21] Distinctive clinicopathological features of Ki-ras mutated colorectal cancers
    Lin, Jen-Kou
    Chang, Shih-Ching
    Wang, Huann-Sheng
    Yang, Shung-Haur
    Jiang, Jeng-Kai
    Chen, Wei-Chone
    Lin, Tzu-Chen
    Li, Anna Fen-Yau
    JOURNAL OF SURGICAL ONCOLOGY, 2006, 94 (03) : 234 - 241
  • [22] Ras signaling pathway proteins as therapeutic targets
    Adjei, AA
    CURRENT PHARMACEUTICAL DESIGN, 2001, 7 (16) : 1581 - 1594
  • [23] Effects of overexpression of cellular ras vs. mutated ras
    Murphy, SK
    Kareem, R
    Lai, Y
    Worobiej, J
    MOLECULAR BIOLOGY OF THE CELL, 2000, 11 : 242A - 242A
  • [24] Ras-signaling is essential for lens growth and development
    Reneker, LW
    Overbeek, PA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2002, 43 : U1115 - U1115
  • [25] Canine hemangiosarcoma as a model for RAS-mutated human cancers: Preliminary data
    White, Michelle E.
    Harvey, Garrett
    Rodrigues, Lucas
    Schwalbach, Chase
    Girimonte, Dorothy
    Miller, Aubrey
    Hull, Abigail
    Lambert, Lindsay
    Lopes, Christina
    Post, Gerald
    MOLECULAR CANCER RESEARCH, 2023, 21 (05)
  • [26] Hyperactive Ras as a therapeutic target in neurofibromatosis type 1
    Weiss, B
    Bollag, G
    Shannon, K
    AMERICAN JOURNAL OF MEDICAL GENETICS, 1999, 89 (01): : 14 - 22
  • [27] RAS amplified colorectal cancers are enriched in RAS-WT, BRAF-WT, MSS tumors and may predict for anti-EGFR resistance.
    Fakih, Marwan
    Sandhu, Jaideep Singh
    Wang, Chongkai
    Ali, Siraj Mahamed
    Schrock, Alexa Betzig
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (04)
  • [28] Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers
    Jiang, Jingjing
    Jiang, Lingyan
    Maldonato, Benjamin J.
    Wang, Yingyun
    Holderfield, Matthew
    Aronchik, Ida
    Winters, Ian P.
    Salman, Zeena
    Blaj, Cristina
    Menard, Marie
    Brodbeck, Jens
    Chen, Zhe
    Wei, Xing
    Rosen, Michael J.
    Gindin, Yevgeniy
    Lee, Bianca J.
    Evans, James W.
    Chang, Stephanie
    Wang, Zhican
    Seamon, Kyle J.
    Parsons, Dylan
    Cregg, James
    Marquez, Abby
    Tomlinson, Aidan C. A.
    Yano, Jason K.
    Knox, John E.
    Quintana, Elsa
    Aguirre, Andrew J.
    Arbour, Kathryn C.
    Reed, Abby
    Gustafson, W. Clay
    Gill, Adrian L.
    Koltun, Elena S.
    Wildes, David
    Smith, Jacqueline A. M.
    Wang, Zhengping
    Singh, Mallika
    CANCER DISCOVERY, 2024, 14 (06) : 994 - 1017
  • [29] RAS MEMBRANE TARGETING IS ESSENTIAL FOR GLUCOSE SIGNALING BUT NOT FOR VIABILITY IN YEAST
    BHATTACHARYA, S
    CHEN, L
    BROACH, JR
    POWERS, S
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (07) : 2984 - 2988
  • [30] The Ras signaling pathway is essential for notochord induction in ascidian embryos
    Nakatani, Y
    Koide, H
    Kaziro, Y
    Nishida, H
    DEVELOPMENTAL BIOLOGY, 1997, 186 (02) : B36 - B36