Recent investigations of bioactive natural products from endophytic, marine-derived, insect pathogenic fungi and Thai medicinal plants

被引：4

作者：

Mahidol, Chulabhorn ^{[1
,2
]}

Kittakoop, Prasat ^{[1
,2
]}

Prachyawarakorn, Vilailak ^{[1
,2
]}

Pailee, Phanruethai ^{[1
,2
]}

Prawat, Hunsa ^{[1
,2
]}

Ruchirawat, Somsak ^{[1
,2
]}

机构：

[1] Chulabhorn Grad Inst, Chulabhorn Res Inst, Bangkok 10210, Thailand

[2] Ctr Excellence Environm Hlth & Toxicol EHT, Bangkok 10210, Thailand

来源：

PURE AND APPLIED CHEMISTRY | 2014年 / 86卷 / 06期

关键词：

biodiversity; biological activity; fungi; IUPAC Congress-44; Life Chemistry; marine chemistry; medicinal plants; natural products; DOTHIDEOMYCETE SP LRUB20; SPONGE IANTHELLA-BASTA; PAPUA-NEW-GUINEA; CURVULARIDES A-E; AIGIALOMYCIN-D; IN-VITRO; HIRSUTELLONE B; CHAMIGRANE ENDOPEROXIDES; DESMOS-COCHINCHINENSIS; ABSOLUTE-CONFIGURATION;

D O I：

10.1515/pac-2013-1206

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Living organisms in Thailand are very diverse due to the unique geographical location of Thailand. The diversity of Thai bioresources has proven to be a rich source of biologically active compounds. The present review covers bioactive substances from Thai endophytic, marine-derived, insect pathogenic fungi and medicinal plants. Many new compounds isolated from Thai bioresources have diverse skeletons belonging to various classes of natural products. These compounds exhibited an array of biological activities, and some are of pharmaceutical interest. Bioactive compounds from Thai bioresources have not only attracted organic chemists to develop strategies for total synthesis, but also attracted (chemical) biologists to investigate the mechanisms of action. The chemistry and biology of some selected compounds are also discussed in this review.

引用

页码：979 / 993

页数：15

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