Discovery of potent and slow-binding inhibitors of α-fucosidase.

被引:0
|
作者
Chang, CF
Ho, CW
Wu, CY
Wong, CH
Lin, CH
机构
[1] Acad Sinica, Genom Res Ctr, Taipei 115, Taiwan
[2] Acad Sinica, Inst Biol Chem, Taipei 115, Taiwan
[3] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA USA
[4] Scripps Res Inst, Dept Chem, La Jolla, CA USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
041-CARB
引用
收藏
页码:U269 / U269
页数:1
相关论文
共 50 条
  • [31] The influence of product instability on slow-binding inhibition
    Garrido-del Solo, C
    Yago, JM
    García-Moreno, M
    Havsteen, BH
    García-Cánovas, F
    Varón, R
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2005, 20 (04) : 309 - 316
  • [33] 4-substituted resorcinols (sulfite alternatives) as slow-binding inhibitors of tyrosinase catecholase activity
    Jimenez, M
    GarciaCarmona, F
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1997, 45 (06) : 2061 - 2065
  • [34] Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L
    Shah, Parag P.
    Myers, Michael C.
    Beavers, Mary Pat
    Purvis, Jeremy E.
    Jing, Huiyan
    Grieser, Heather J.
    Sharlow, Elizabeth R.
    Napper, Andrew D.
    Huryn, Donna M.
    Cooperman, Barry S.
    Smith, Amos B., III
    Diamond, Scott L.
    MOLECULAR PHARMACOLOGY, 2008, 74 (01) : 34 - 41
  • [35] Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site
    Venäläinen, JI
    Juvonen, RO
    Garcia-Horsman, JA
    Wallén, EAA
    Christiaans, JAM
    Jarho, EM
    Gynther, J
    Männistö, PT
    BIOCHEMICAL JOURNAL, 2004, 382 : 1003 - 1008
  • [36] In Vitro Pharmacokinetic Optimizations of AM2-S31N Channel Blockers Led to the Discovery of Slow-Binding Inhibitors with Potent Antiviral Activity against Drug-Resistant Influenza A Viruses
    Wang, Yuanxiang
    Hu, Yanmei
    Xu, Shuting
    Zhang, Yongtao
    Musharrafieh, Rami
    Hau, Raymond Kin
    Ma, Chunlong
    Wang, Jun
    JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (03) : 1074 - 1085
  • [37] Rapid discovery of potent α-fucosidase inhibitors by in situ screening of a library of (pyrrolidin-2-yl)triazoles
    Elias-Rodriguez, Pilar
    Moreno-Clavijo, Elena
    Carmona, Ana T.
    Moreno-Vargas, Antonio J.
    Robina, Inmaculada
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (31) : 5898 - 5904
  • [38] THE KINETICS OF SLOW-BINDING AND SLOW, TIGHT-BINDING INHIBITION - THE EFFECTS OF SUBSTRATE DEPLETION
    WALEY, SG
    BIOCHEMICAL JOURNAL, 1993, 294 : 195 - 200
  • [39] Rapid discovery of potent α-fucosidase inhibitors by in situ screening of a library of (pyrrolidin-2-yl)triazoles
    Elías-Rodríguez, Pilar
    Moreno-Clavijo, Elena
    Carmona, Ana T.
    Moreno-Vargas, Antonio J.
    Robina, Inmaculada
    Organic and Biomolecular Chemistry, 2014, 12 (31): : 5898 - 5904
  • [40] Slow-binding inhibition - A theoretical and practical course for students
    Golicnik, M
    Stojan, J
    BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, 2004, 32 (04) : 228 - 235