Improved synthesis of 2-amino-1,2,4-triazolo[1,5-a]pyrimidines

被引：14
|
作者：
Chernyshev, V. M. [1 ]
Sokolov, A. N. [1 ]
Taranushich, V. A. [1 ]
机构：
[1] S Russian State Tech Univ, Rostov Na Donu, Russia
来源：
RUSSIAN JOURNAL OF APPLIED CHEMISTRY | 2006年 / 79卷 / 07期
关键词：
D O I：
10.1134/S1070427206070172
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An improved procedure is suggested for preparing 2-amino-1,2,4-triazolo[1,5-a]pyrimidines from 3,5-diamino-1,2,4-triazole and unsaturated aromatic ketones, with acetyl protection of the amino group in the step of oxidation of 2-amino-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines.
引用
收藏
页码：1134 / 1137
页数：4
相关论文
共 50 条
  • [41] Stable salts of 1,2,4-triazolo[1,5-a]pyrimidinium
    Kolos, NN
    Orlov, VD
    Paponov, BV
    Shishkin, OV
    Baumer, SV
    Kvashnitskaya, NA
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1999, (06): : 796 - 804
  • [42] AROMATIC SUBSTITUTED 1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE
    DESENKO, SM
    ORLOV, VD
    GETMANSKY, NV
    SHISHKIN, OV
    LINDEMAN, SV
    STRUCHKOV, YT
    DOKLADY AKADEMII NAUK, 1992, 324 (04) : 801 - 804
  • [43] MECHANISM OF ACTION OF THE 1,2,4-TRIAZOLO[1,5A]PYRIMIDINES
    GERWICK, BC
    LONEY, V
    SUBRAMANIAN, M
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1987, 194 : 163 - AGRO
  • [44] Synthesis and Biological Evaluation of New 1,2,4-Triazolo[1,5-a] pyridine and 1,2,4-Triazolo[1,5-a] isoquinoline Derivatives Bearing Diphenyl Sulfide Moiety as Antimicrobial Agents
    El-Adasy, Abu-Bakr A.
    Hussein, Abd El-Haleem M.
    Ishak, Esam A.
    Hafiz, Ibrahim S. A.
    Gawish, Emad H.
    Elapasery, Morsy A.
    El-Gaby, Mohamed S. A.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2021, 64 (02): : 913 - 921
  • [45] REACTION OF 6-NITRO-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINES WITH BENZYLAMINE - AN UNUSUAL SYNTHESIS OF 1-HYDROXYIMIDAZOLES
    RUSINOV, VL
    KUSHNIR, MN
    CHUPAKHIN, ON
    ALEXANDROV, GG
    MENDELEEV COMMUNICATIONS, 1993, (05) : 213 - 214
  • [46] SYNTHESIS OF STEROIDAL [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR ANTIPROLIFERATIVE ACTIVITIES
    Fan, Ning-Juan
    Tang, Jiang-Jiang
    Li, Yuan-Feng
    Bai, Yu-Bin
    Zhao, Xiao-Min
    HETEROCYCLES, 2019, 98 (06) : 822 - 831
  • [47] 1,2,4-TRIAZOLO[1,5-A]PYRIMIDINES FROM 3-FORMYL-2,5-DIMETHOXYTETRAHYDROFURANS
    VARTANYAN, MM
    ELISEEV, OL
    BREZHNEV, LY
    KARAKHANOV, RA
    RUSSIAN CHEMICAL BULLETIN, 1993, 42 (01) : 210 - 210
  • [48] Synthesis of pyrazolo[1,5-a]-, 1,2,4-triazolo[1,5-a]- and imidazo[1,2-a]pyrimidines related to zaleplon, a new drug for the treatment of insomnia
    Mustazza, C
    Del Giudice, MR
    Borioni, A
    Gatta, F
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2001, 38 (05) : 1119 - 1129
  • [49] CHEMOTHERAPEUTIC-AGENTS .13. SYNTHESIS OF 2-PYRIDYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINES AS ANTIMICROBIAL AGENT
    RAM, VJ
    KUSHWAHA, DS
    MISHRA, L
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1989, 28 (03): : 242 - 246
  • [50] Ultrasound irradiation promotes the synthesis of new 1,2,4-triazolo [1,5-a]pyrimidine
    Frizzo, Clarissa P.
    Scapin, Elisandra
    Marzari, Mara R. B.
    Muenchen, Taiana S.
    Zanatta, Nilo
    Bonacorso, Helio G.
    Buriol, Lilian
    Martins, Marcos A. P.
    ULTRASONICS SONOCHEMISTRY, 2014, 21 (03) : 958 - 962
12345