Synthesis and Antioxidant and Cytotoxic Activity of New Dihydroquercetin Derivatives

被引:4
|
作者
Knyazev, V. V. [1 ]
Rogovskii, V. S. [1 ]
Sveshnikova, E. D. [1 ]
Semeikin, A. V. [1 ]
Matyushin, A. I. [1 ]
Fedotcheva, T. A. [1 ]
Shimanovskii, N. L. [1 ]
Pozdeev, A. O. [2 ]
Koroteev, A. M. [2 ]
Koroteev, M. P. [2 ]
机构
[1] NI Pirogov Russian Natl Res Med Univ, 9A-1 Bolshaya Pirogovskaya St, Moscow 119435, Russia
[2] Moscow State Pedag Univ, Inst Biol & Chem, 6-2 Kibalchicha St, Moscow 129164, Russia
关键词
dihydroquercetin; 3-monoacylated dihydroquercetin derivatives; antioxidant activity; cytotoxic activity; taxifolin; ABTS test; HeLa cells; QUERCETIN;
D O I
10.1007/s11094-018-1791-8
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Aseries of new 3-monoacylated dihydroquercetin derivatives were synthesized and possessed antioxidant and cytotoxic activity with respect to HeLa tumor cells.
引用
收藏
页码:205 / 208
页数:4
相关论文
共 50 条
  • [31] SYNTHESIS AND INVITRO CYTOTOXIC ACTIVITY OF NEW N-DIAZOACETYLGLYCINE DERIVATIVES
    DELLALOGGIA, R
    FURLANI, A
    SAVASTANO, F
    SCARCIA, V
    EXPERIENTIA, 1976, 32 (05): : 636 - 638
  • [32] Synthesis of new calix[4]arene derivatives and evaluation of their cytotoxic activity
    Oguz, Mehmet
    Yildirim, Ayse
    Durmus, Irem Mukaddes
    Karakurt, Serdar
    Yilmaz, Mustafa
    MEDICINAL CHEMISTRY RESEARCH, 2022, 31 (01) : 52 - 59
  • [33] Synthesis of new calix[4]arene derivatives and evaluation of their cytotoxic activity
    Mehmet Oguz
    Ayse Yildirim
    Irem Mukaddes Durmus
    Serdar Karakurt
    Mustafa Yilmaz
    Medicinal Chemistry Research, 2022, 31 : 52 - 59
  • [34] Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives
    Ferrari, Erika
    Lazzari, Sandra
    Marverti, Gaetano
    Pignedoli, Francesca
    Spagnolo, Ferdinando
    Saladini, Monica
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (08) : 3043 - 3052
  • [35] Synthesis and Cytotoxic Evaluation for Some New Dihydropyrimidinone Derivatives for Anticancer Activity
    Reddy, Onteddu Surendranatha
    Suryanarayana, Ch Venkata
    Sharmila, N.
    Ramana, G. V.
    Anuradha, V.
    Babu, B. Hari
    LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 10 (08) : 699 - 705
  • [36] Microwave assisted synthesis and cytotoxic activity evaluations of new benzimidazole derivatives
    Hue Thi Buu Bui
    Quy Thi Kim Ha
    Oh, Won Keun
    Duy Duc Vo
    Yen Nguyen Tram Chau
    Cuc Thi Kim Tu
    Em Canh Pham
    Phuong Thao Tran
    Loan Thi Tran
    Hieu Van Mai
    TETRAHEDRON LETTERS, 2016, 57 (08) : 887 - 891
  • [37] Dihydroquercetin: known antioxidant-new inhibitor of alpha-amylase activity
    Zaynullin, Radik A.
    Kunakova, Raikhana V.
    Khusnutdinova, Elza K.
    Yalaev, Bulat I.
    Patricia Segura-Ceniceros, E.
    Chavez-Gonzalez, Monica L.
    Martinez-Hernandez, Jose L.
    Gernet, Marina V.
    Batashov, Evgeny S.
    Ilyina, Anna
    MEDICINAL CHEMISTRY RESEARCH, 2018, 27 (03) : 966 - 971
  • [38] Synthesis, Antioxidant, and Cytotoxic Activities of New 1,3,4-Thiadiazoldiazenylacrylonitrile Derivatives
    Katouah, Hanadi A.
    POLYCYCLIC AROMATIC COMPOUNDS, 2023, 43 (09) : 7808 - 7827
  • [39] Synthesis of new morpholine-connected pyrazolidine derivatives and their antimicrobial, antioxidant, and cytotoxic activities
    Kumar, Radhakrishnan Surendra
    Moydeen, Meera
    Al-Deyab, Salem S.
    Manilal, Aseer
    Idhayadhulla, Akbar
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (01) : 66 - 71
  • [40] DIHYDROQUERCETIN AS AN ANTIOXIDANT
    KURTH, EF
    CHAN, FL
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1951, 28 (10) : 433 - 436