Lymphoplasmacytoid Lymphoma in a Cow

被引:5
|
作者
Honda, Hidetsugu [2 ]
Ishikawa, Yoshiharu [1 ]
Kadota, Koichi [1 ]
机构
[1] Natl Inst Anim Hlth, Hokkaido Res Stn, Sapporo, Hokkaido 0620045, Japan
[2] Toyama Prefecture, Agr Technol Div, Toyama 9308501, Japan
来源
JOURNAL OF VETERINARY MEDICAL SCIENCE | 2009年 / 71卷 / 05期
关键词
cattle; immunoglobulin; lymphoma; LEUKEMIA;
D O I
10.1292/jvms.71.673
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Lymphoplasmacytoid lymphoma was found in an 8-year-old Holstein cow uninfected with bovine leukemia virus (BLV). The neoplastic tissue was composed of lymphoid and plasmacytoid cells, and intracytoplasmic IgM (lambda) was detected in the latter. The diagnosis was based on the presence of small lymphoid cells and the expression of CD5, which were suggestive of a close relationship with chronic lymphocytic leukemia. Areas of immunoblastoid cells were reminiscent of histologic progression into immunoblastic lymphoma. The neoplastic cells at different stages of differentiation were distinct front those of BLV-associated pleomorphic lymphoma.
引用
收藏
页码:673 / 676
页数:4
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