New Dammarane-Type Saponins from the Roots of Panax notoginseng

被引:18
|
作者
Qiu, Li [1 ,2 ,3 ]
Jiao, Yang [3 ]
Huang, Gui-Kun [3 ]
Xie, Ji-Zhao [3 ]
Miao, Jian-Hua [2 ]
Yao, Xin-Sheng [1 ]
机构
[1] Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
[2] Inst Guangxi Med Plant, Nanning 530023, Guangxi, Peoples R China
[3] Guangxi Med Univ, Sch Pharmaceut Sci, Nanning 530021, Guangxi, Peoples R China
关键词
Panax notoginseng; Dammarane; Saponins; Notoginsenoside; Ginsenosides; TRITERPENE OLIGOGLYCOSIDES; BIOACTIVE SAPONINS; SANCHI-GINSENG; BURK CHEN; F.H; DRIED ROOT; GLYCOSIDES; LIPOPOLYSACCHARIDE; LEAVES; ACID;
D O I
10.1002/hlca.201300155
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Three new dammarane-type triterpenoid saponins, 1-3, were isolated and identified as (20S)-20-O-[-D-xylopyranosyl-(16)--D-glucopyranosyl-(16)--D-glucopyranosyl]dammar-24-ene-3,6,12, 20-tetrol (1), (20S)-6-O-[(E)-but-2-enoyl-(16)--D-glucopyranosyl]dammar-24-ene-3,6,12,20-tetrol (2), and (20S)-6-O-[-D-xylopyranosyl-(12)--D-xylopyranosyl]dammar-24-ene-3,6,12,20-tetrol (3) from the roots of Panax notoginseng (Burkill) F.H.Chen (Araliaceae). Their structures were elucidated on the basis of spectroscopic analyses, including 1D- and 2D-NMR techniques and HR-ESI-MS, as well as by acidic hydrolysis.
引用
收藏
页码:102 / 111
页数:10
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