Single-minded CRISPR screening

被引:4
|
作者
Lanning, Bryan R. [1 ]
Vakoc, Christopher R. [1 ]
机构
[1] Cold Spring Harbor Lab, POB 100, Cold Spring Harbor, NY 11724 USA
关键词
GENETIC SCREENS; HUMAN-CELLS; CIRCUITS; SEQ;
D O I
10.1038/nbt.3849
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Transcriptome-wide effects of gene knockouts are screened at the single-cell level by combining high-throughput, single-cell RNA-seq with lentiviral CRISPR libraries.
引用
收藏
页码:339 / 340
页数:3
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