Three-component coupling of benzyne: Domino intermolecular carbopalladation

被引:96
|
作者
Henderson, Jaclyn L.
Edwards, Andrew S.
Greaney, Michael F.
机构
[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland
[2] Organon Res Labs Ltd, Newhouse ML1 5SH, Lanark, Scotland
关键词
D O I
10.1021/ja0615526
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new three-component coupling reaction of benzyne is described that uses two intermolecular carbopalladation reactions to produce 1,2-functionalized benzene derivatives. Copyright © 2006 American Chemical Society.
引用
收藏
页码:7426 / 7427
页数:2
相关论文
共 50 条
  • [31] Metal-Free Three-Component Domino Approach to Phosphonylated Triazolines and Triazoles
    Ahamad, Shakir
    Kant, Ruchir
    Mohanan, Kishor
    ORGANIC LETTERS, 2016, 18 (02) : 280 - 283
  • [32] Catalytic Domino Three-Component Synthesis of Functionalized Heterocycles from Carbon Dioxide
    Shi, Wangyu
    Qiao, Chang
    Benet-Buchholz, Jordi
    Kleij, Arjan W.
    CHEMSUSCHEM, 2024, 17 (06)
  • [33] Ultrasound-assisted a domino three-component reaction to polycyclic selenopyrans synthesis
    Sedighian, Hadi
    Imani, Kaveh
    Bazgir, Ayoob
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2022, 197 (02) : 89 - 95
  • [34] Three-Component (Domino) Reaction Affording Substituted Pyrroloquinazolines: Cyclization Regioselectivity and Stereoselectivity
    Paleta, Oldrich
    Dolensky, Bohumil
    Palecek, Jiri
    Kvicala, Jaroslav
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (07) : 1262 - 1270
  • [35] Selective synthesis of polyfunctionalized hydroisoquinoline derivatives via a three-component domino reaction
    Zhang, Juan-Juan
    Hu, Jun-Die
    Cao, Cheng-Pao
    Dou, Guo-Lan
    Fu, Lei
    Huang, Zhi-Bin
    Shi, Da-Qing
    RSC ADVANCES, 2014, 4 (107) : 62457 - 62464
  • [36] Three-component cascade carbopalladation/Heck cyclization/borylation: facile access to boryl-functionalized indenes
    Sun, Fei
    Zheng, Yiyi
    Wu, Mingxia
    Ji, Hongsen
    Jiang, Zhongyao
    Liu, Chenglin
    Wu, Xin-Xing
    CHEMICAL COMMUNICATIONS, 2024, 60 (62) : 8075 - 8078
  • [37] Nickel-catalyzed regio- and diastereoselective intermolecular three-component coupling of oxabicyclic alkenes with alkynes and organoboronic acids
    Mannathan, Subramaniyan
    Cheng, Chien-Hong
    CHEMICAL COMMUNICATIONS, 2013, 49 (15) : 1557 - 1559
  • [38] Palladium-catalyzed intermolecular three-component coupling of organic halides with Alkynes and alkenes: Efficient synthesis of oligoene compounds
    Shibata, Kana
    Satoh, Tetsuya
    Miura, Masahiro
    ADVANCED SYNTHESIS & CATALYSIS, 2007, 349 (14-15) : 2317 - 2325
  • [39] Direct synthesis of 2-(aminomethyl)indoles through copper(I)-catalyzed domino three-component coupling and cyclization reactions
    Ohno, Hiroaki
    Ohta, Yusuke
    Oishi, Shinya
    Fujii, Nobutaka
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (13) : 2295 - 2298
  • [40] Synthesis of 2-heterocyclic substituted pyrrolidines by copper-catalyzed domino three-component decarboxylative coupling and cyclization reactions
    Jin, Zheng-neng
    Jiang, Hua-jiang
    Wu, Jia-shou
    Gong, Wei-zhong
    Cheng, Yue
    Xiang, Jing
    Zhou, Qi-Zhong
    TETRAHEDRON LETTERS, 2015, 56 (21) : 2720 - 2723