Synthesis, crystal structure and absolute configuration of (+)-(α-hydroxybenzyl)phenylphosphinic acid

被引：0
|
作者：
Cai, JX
Zhou, ZH
Tang, CC [1 ]
Wang, HG
机构：
[1] Nankai Univ, Inst Elemento Organ Chem, State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China
[2] Nankai Univ, Cent Lab, Tianjin 300071, Peoples R China
来源：
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2002年 / 21卷 / 04期
关键词：
alpha-hydroxyphosphinic acid; (+)-(alpha-hydroxybenzyl)phenylphosphinic acid; crystal structure; absolute configuration;
D O I：
暂无
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The title compound (+)-(alpha-hydroxybenzyl)phenylphosphinic acid (C13H13O3P, M-r= 248.20) has been synthesized and characterized by P-31 NMR, H-1 NMR and elemental analysis. X-ray diffraction analysis at 293(2) K indicates that the compound belongs to monoclinic system, space group C2 with cell parameters: a = 23.560(8), b = 6.947(2), c = 7.854(3) Angstrom, beta= 91.273(6)degrees, V = 1285.2(7) Angstrom(3), Z = 4, D-c = 1.283 g/cm(3), F(000) = 520 and mu(MoKalpha) = 0.207 mm(-1). The number of independent reflections amounts to 1991, of which 1507 are observed reflections. The crystal structure has been determined by direct methods (SHELXL-97). The structure parameters are refined by full-matrix least-squares on F-2 to R = 0.0437 and wR = 0.0893. The flack x parameter is - 0.0001. The absolute configuration of the a-carbon in the title compound is S.
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收藏
页码：368 / 370
页数：3
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