Enterovirus D68 infection among hospitalized children with severe acute respiratory illness in El Salvador and Panama, 2012-2013

被引:3
|
作者
Biggs, Holly M. [1 ]
Nix, W. Allan [1 ]
Zhang, Jing [1 ]
Rogers, Shannon [1 ]
Clara, Wilfrido [1 ]
Jara, Jorge H. [2 ]
Gonzalez, Rosalba [3 ]
Luciani, Kathia [4 ]
Brizuela, Yarisa Sujey [5 ]
Estripeaut, Dora [6 ]
Castillo, Juan Miguel [7 ]
De Leon, Tirza [8 ]
Corro, Mary [4 ]
Vergara, Ofelina [6 ]
Rauda, Rafael [7 ]
Chong, Evens G. [8 ]
Watson, John T. [1 ]
Azziz-Baumgartner, Eduardo [1 ]
Gerber, Susan, I [1 ]
Tong, Suxiang [1 ]
Dawood, Fatimah S. [1 ]
机构
[1] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Atlanta, GA 30333 USA
[2] Univ Valle Guatemala, Ctr Estudios Salud, Guatemala City, Guatemala
[3] Gorgas Mem Inst Hlth Studies, Panama City, Panama
[4] Hosp Especialidades Pediat Omar Torrijos, Panama City, Panama
[5] Hosp San Juan Dios, San Miguel, El Salvador
[6] Hosp Nino, Panama City, Panama
[7] Hosp San Juan Dios, Santa Ana, El Salvador
[8] Hosp Materno Infantil Jose Domingo De Obaldia, David, Panama
关键词
acute respiratory illness; Central America; El Salvador; Enterovirus D68; Panama; respiratory virus; UNITED-STATES; JULY-OCTOBER; SURVEILLANCE; PNEUMONIA;
D O I
10.1111/irv.12815
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We assessed EV-D68 epidemiology and phylogenetics among children aged <= 9 years hospitalized with severe acute respiratory illnesses at five sites in Panama and El Salvador during 2012-2013. Respiratory specimens positive for enterovirus or rhinovirus were tested by real-time RT-PCR for EV-D68, and partial VP1 gene sequences were determined. Of 715 enrolled children, 17 from sites in both countries were EV-D68-positive and commonly had a history of asthma or wheezing. Phylogenetically, 15 of 16 sequences fell into Clade B1, and one into Clade A2. The Central American EV-D68s were closely related genetically to contemporaneous strains from North America, South America, and the Caribbean.
引用
收藏
页码:181 / 187
页数:7
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