A Pungent and Painful Toxin

被引:2
|
作者
Green, Dustin [1 ]
Dong, Xinzhong [1 ,2 ]
机构
[1] Johns Hopkins Univ, Sch Med, Solomon H Snyder Dept Neurosci, Dept Neurosurg,Dept Dermatol,Ctr Sensory Biol, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Howard Hughes Med Inst, Baltimore, MD 21205 USA
关键词
ION CHANNELS;
D O I
10.1016/j.cell.2019.08.016
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Cell, King et al. (2019) have discovered a cell penetrating peptide isolated from the venom of the Australian Black Rock scorpion that activates the TRPA1 receptor in a unique way to induce pain. Their findings offer new insights into how animals evolved venoms to target specific ion channel functions.
引用
收藏
页码:1279 / 1281
页数:4
相关论文
共 50 条
  • [21] Beneficial effects of botulinum toxin type A for patients with painful tic convulsif
    Micheli, F
    Scorticati, MC
    Raina, G
    CLINICAL NEUROPHARMACOLOGY, 2002, 25 (05) : 260 - 262
  • [22] A case of painful hemimasticatory spasm with facial hemihypertrophy responsive to botulinum toxin
    Ma, H-I.
    Kim, Y. J.
    Kim, J. -H.
    Oh, M. -S.
    Lee, B. -C.
    MOVEMENT DISORDERS, 2008, 23 (01) : S235 - S235
  • [23] Treatment of painful limbs/moving extremities with botulinum toxin type A injections
    Eisa, Mahmood
    Singer, Carlos
    Sengun, Cenk
    Russel, Angela
    Jabbari, Bahman
    Papapetropoulos, Spiridon
    EUROPEAN NEUROLOGY, 2008, 60 (02) : 104 - 106
  • [24] Botulinum toxin type A for the treatment of painful legs moving toes syndrome
    Trieschmann, ME
    Fernandez, HH
    MOVEMENT DISORDERS, 2003, 18 (09) : 1094 - 1095
  • [25] Botulinum toxin for painful limbs moving extremities: Are distal injections critical?
    Alvarez, Maria V.
    Evidente, Virgilio Gerald H.
    Grogan, Patrick M.
    PARKINSONISM & RELATED DISORDERS, 2010, 16 (10) : 693 - 694
  • [26] OFF PAINFUL DYSTONIA IN PARKINSONS-DISEASE TREATED WITH BOTULINUM TOXIN
    PACCHETTI, C
    ALBANI, G
    MARTIGNONI, E
    GODI, L
    ALFONSI, E
    NAPPI, G
    MOVEMENT DISORDERS, 1995, 10 (03) : 333 - 336
  • [27] Evaluation of botulinum toxin type B for a patient with painful muscle spasms
    Smith, H
    Dubin, A
    Tang, J
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 : R42 - R42
  • [28] A Pilot Study of Botulinum Toxin for Interstitial Cystitis/Painful Bladder Syndrome
    Gottsch, Henry P.
    Miller, Jane L.
    Yang, Claire C.
    Berger, Richard E.
    NEUROUROLOGY AND URODYNAMICS, 2011, 30 (01) : 93 - 96
  • [29] Painful shoulder syndrome for lesion of rotator cuff: management with botullinum toxin
    Juan Jose, Arriaga
    Sandra, Quinones
    Ortiz Araceli, Toriz
    Nancy, Bertado
    Ana Belen, Garcia Sierra
    Noel, Plascencia
    Lilia, Nunez
    REVISTA MEXICANA DE NEUROCIENCIA, 2008, 9 (04): : 261 - 267
  • [30] Botulinum Toxin-A for Painful Diabetic Neuropathy: A Meta-Analysis
    Lakhan, Shaheen E.
    Velasco, Dominic N.
    Tepper, Deborah
    PAIN MEDICINE, 2015, 16 (09) : 1773 - 1780