Molecular Diagnosis of Hematopoietic and Lymphoid Neoplasms

被引：5
|
作者：
Jevremovic, Dragan [1 ]
Viswanatha, David S. [1 ]
机构：
[1] Mayo Clin, Dept Lab Med & Pathol, Div Hematopathol, Rochester, MN 55905 USA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2009年 / 23卷 / 04期
关键词：
Gene rearrangements; Clonality; Chromosome translocation; Polymerase chain reaction; Fluorescence in situ hybridization; Minimal residual disease; POLYMERASE-CHAIN-REACTION; MINIMAL RESIDUAL DISEASE; ACUTE LYMPHOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; B-CELL LYMPHOMA; TIME QUANTITATIVE PCR; ACUTE PROMYELOCYTIC LEUKEMIA; IN-SITU HYBRIDIZATION; HARMONIZING CURRENT METHODOLOGY; CHRONIC LYMPHOCYTIC-LEUKEMIA;
D O I：
10.1016/j.hoc.2009.04.011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This chapter summarizes the significance and molecular diagnostic detection of genetic abnormalities commonly associated with hematolymphoid neoplasms. Methodologic aspects of laboratory diagnosis are presented, as well as discussion of multiparameter genotyping of tumors for prognosis and the role of minimal residual disease monitoring in specific neoplasms.
引用
收藏
页码：903 / +
页数：32
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