It's not over till the last glomerulus forms

被引:5
|
作者
Thomas, Rosemary [1 ]
Kaskel, Frederick J. [1 ]
机构
[1] Childrens Hosp Montefiore, Div Pediat Nephrol, Albert Einstein Coll Med, Bronx, NY 10467 USA
关键词
EXTRAUTERINE GROWTH RESTRICTION; MATERNAL PROTEIN RESTRICTION; GESTATIONAL-AGE; PRETERM;
D O I
10.1038/ki.2009.181
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The Brenner hypothesis postulated that low birth weight and decreased nephron number at birth are linked to chronic kidney disease and systemic hypertension in adulthood. To date, little is known about the effect of extrauterine growth retardation (EUGR) on adult kidney disease. Bacchetta et al. present novel data using inulin to show a decrease in renal function for premature children with EUGR. The role of protein nutrition and timing in nephrogenesis is discussed.
引用
收藏
页码:361 / 363
页数:3
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