An efficient synthesis of enantiomerically pure unnatural aryl glycinols and aryl glycines

被引:12
|
作者
Ku, Hui-Young
Jung, Junyang
Kim, Soo-Hyun
Kim, Hee Yeon
Ahn, Kyo Han
Kim, Sung-Gon
机构
[1] Pohang Univ Sci & Technol, Dept Chem, Pohang 790784, South Korea
[2] Pohang Univ Sci & Technol, Ctr Integrated Mol Syst, Div Mol & Life Sci, Pohang 790784, South Korea
[3] Korea Res Inst Chem Technol, Div Med Sci, Taejon 305600, South Korea
关键词
D O I
10.1016/j.tetasy.2006.03.031
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A quick route to enantiomerically pure unnatural aryl glycinols and aryl glycines has been established based on an asymmetric azidation reaction using a chiral benzosultam auxiliary. The synthesis of aryl glycinols involves three steps starting from arylacetic acids, and the chiral auxiliary can be readily recovered. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1111 / 1115
页数:5
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