Preparation and Characterization of Porous Scaffolds Consisted of Hydroxyapatite, Polysaccharides and Collagen for Cartilage Tissue Engineering

被引：1
|
作者：
Adegawa, Takuro [1 ]
Ohyabu, Yoshimi [1 ,2 ]
Uemura, Toshimasa [2 ]
Yoshioka, Tomohiko [1 ]
Shinozaki, Kazuo [1 ]
Tanaka, Junzo [1 ]
机构：
[1] Tokyo Inst Technol, Dept Met & Ceram Sci, Meguro Ku, 2-12-1 S7-6, Tokyo 1528550, Japan
[2] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058562, Japan
来源：
BIOCERAMICS 21 | 2009年 / 396-398卷
关键词：
cartilage; scaffold; hydroxyapatite; polysaccharide; chondroitinsulfate; collagen; NANOCOMPOSITES; MATRICES; CELLS;
D O I：
10.4028/www.scientific.net/KEM.396-398.707
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Porous scaffolds, consisted of hydroxyapatite (HAp), chondroitinsulfate (ChS) and collagen, were prepared by freeze-drying technique. HAp/ChS composite particles were incorporated into a collagen matrix. Scanning electron microscope (SEM) observations showed that the porous scaffolds involved interconnected pores whose size was 80-200 mu m in diameter. The HAp/ChS particles were homogeneously distributed in the collagen matrix. Surface area of the scaffolds was increased by the incorporation of the particles. Compression tests in phosphate buffer saline indicated that the porous scaffolds had elastic property and had larger compressive modulus than the pure collagen scaffold. The porous scaffolds obtained in this study could be useful for a cartilage tissue engineering.
引用
收藏
页码：707 / 710
页数：4
相关论文
共 50 条
  • [21] Electrospinning of highly porous scaffolds for cartilage tissue engineering
    Thorvaldsson, A.
    Stenhamre, H.
    Gatenholm, P.
    Walkenstrom, P.
    TISSUE ENGINEERING PART A, 2008, 14 (05) : 845 - 846
  • [22] Tissue engineering of collagen scaffolds crosslinked with plant based polysaccharides
    Rohit Rekulapally
    K. Udayachandrika
    Sirisha Hamlipur
    Anuja Sasidharan Nair
    Biswajit Pal
    Shashi Singh
    Progress in Biomaterials, 2021, 10 : 29 - 41
  • [23] Tissue engineering of collagen scaffolds crosslinked with plant based polysaccharides
    Rekulapally, Rohit
    Udayachandrika, K.
    Hamlipur, Sirisha
    Sasidharan Nair, Anuja
    Pal, Biswajit
    Singh, Shashi
    PROGRESS IN BIOMATERIALS, 2021, 10 (01) : 29 - 41
  • [24] Interconnected collagen porous scaffolds prepared with sacrificial PLGA sponge templates for cartilage tissue engineering
    Xie, Yan
    Lee, Kyubae
    Wang, Xiuhui
    Yoshitomi, Toru
    Kawazoe, Naoki
    Yang, Yingnan
    Chen, Guoping
    JOURNAL OF MATERIALS CHEMISTRY B, 2021, 9 (40) : 8491 - 8500
  • [25] Zone-Specific Collagen Alignment in Porous Polymer Scaffolds for Articular Cartilage Tissue Engineering
    Steele, J. A.
    St-Pierre, J.
    McCullen, S. D.
    Meinert, C.
    You, A. Y.
    Theodoropoulos, C.
    Autefage, H.
    Klein, T. J.
    Dunlop, I. E.
    Saifzadeh, S.
    Steck, R.
    Woodruff, M. A.
    Stevens, M. M.
    TISSUE ENGINEERING PART A, 2015, 21 : S111 - S111
  • [26] Preparation and Characterization of Nanocomposite Scaffolds (Collagen/β-TCP/SrO) for Bone Tissue Engineering
    Hamid Goodarzi
    Sameereh Hashemi-Najafabadi
    Nafiseh Baheiraei
    Fatemeh Bagheri
    Tissue Engineering and Regenerative Medicine, 2019, 16 : 237 - 251
  • [27] Preparation and Characterization of Nanocomposite Scaffolds (Collagen/β-TCP/SrO) for Bone Tissue Engineering
    Goodarzi, Hamid
    Hashemi-Najafabadi, Sameereh
    Baheiraei, Nafiseh
    Bagheri, Fatemeh
    TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2019, 16 (03) : 237 - 251
  • [28] Preparation of collagen scaffolds with controlled pore structures and improved mechanical property for cartilage tissue engineering
    Zhang, Qin
    Lu, Hongxu
    Kawazoe, Naoki
    Chen, Guoping
    JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2013, 28 (05) : 426 - 438
  • [29] Preparation of PLGA-collagen hybrid scaffolds with controlled pore structures for cartilage tissue engineering
    Putri, Nur Rofiqoh Eviana
    Wang, Xiuhui
    Chen, Ying
    Li, Xiaomeng
    Kawazoe, Naoki
    Chen, Guoping
    PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL, 2020, 30 (05) : 642 - 650
  • [30] Preparation of PLGA-collagen hybrid scaffolds with controlled pore structures for cartilage tissue engineering
    Nur Rofiqoh Eviana Putri
    Xiuhui Wang
    Ying Chen
    Xiaomeng Li
    Naoki Kawazoe
    Guoping Chen
    Progress in Natural Science:Materials International, 2020, 30 (05) : 642 - 650
12345