Nanocrystalline copper(II) oxide catalyzed three-component coupling of aromatic amines, beta-ketoesters and cinnamaldehyde to afford the corresponding 1,4-dihydropyridines in moderate to good yields under mild conditions is described. The catalyst can be recovered and reused for four cycles with almost consistent activity. (c) 2008 Elsevier B.V. All rights reserved.
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Natl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, SingaporeNatl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, Singapore
Murugan, R.
Ramamoorthy, K.
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Natl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, SingaporeNatl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, Singapore
Ramamoorthy, K.
Sundarrajan, S.
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Natl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, SingaporeNatl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, Singapore
Sundarrajan, S.
Ramakrishna, S.
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Natl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, Singapore
Inst Mat Res & Engn, Singapore 117602, Singapore
King Saud Univ, Riyadh 11451, Saudi ArabiaNatl Univ Singapore, NUSNNI, HEM Lab, Singapore 117576, Singapore