Synthesis of novel asymmetrical 1,4-dihydropyridine derivatives

被引：5
|
作者：
Zenouz, AM [1 ]
Oskuie, MR [1 ]
Mollazadeh, S [1 ]
机构：
[1] Azarbaijan Univ Tarbiat Moallem, Dept Chem, Fac Sci, Tabriz, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 22期
关键词：
calcium channel blockers; 1,4-dihydropyridines; Hantzsch esters; Hantzsch synthesis;
D O I：
10.1080/00397910500297305
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Asymmetrical 1,4-dihydropyridine esters 3a and 3i-k were synthesized from the symmetrical precursor 1 through the intermediate 2-bromomethyl derivative 2. Then, compound 3a was subjected to a different transformation for preparation of 1,4-dihydropyridine derivatives 3b-h.
引用
收藏
页码：2895 / 2903
页数：9
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