Role of Adhesion Molecules Early After Hypoxic-Ischemic Brain Injury in Preterm Lambs

被引：0

作者：

Alonso-Alconada, D. ^{[1
]}

Alvarez, A. ^{[1
]}

Goni de Cerio, F. ^{[1
]}

Alvarez, F. J.

Rey-Santano, M. C.

Mielgo, V. E.

Valls i Soler, A.

Hilario, E. ^{[1
]}

机构：

[1] Univ Basque Country, Sch Med, Bilbao, Spain

来源：

PROCEEDINGS OF THE XXI EUROPEAN CONGRESS OF PERINATAL MEDICINE | 2008年

关键词：

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

To evaluate the expression levels of ICAM-1, VCAM-1, VLA-4 and fibronectin after brain injury induced by partial occlusion of the umbilical cord in fetal lambs. We found, in the first moments after HI brain injury, a decrease in the expression of these adhesion molecules, with the exception of the ICAM-1 whose levels showed no changes. These data suggest that de novo synthesized adhesion molecules will not be detected until after a period of 4 hours or more, whereas ICAM-1 maintains its expression in a constitutive form.

引用

页码：169 / 174

页数：6

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