Targeting GPCR signaling in HER2+breast cancer suppresses cancer stem cell tumorigenicity and sensitizes HER2-targeted therapies

被引：0
|
作者：
Wang, Wei [1 ]
Bhargava, Dharmendra [1 ]
Ye, Yuan Chao [1 ]
Chen, Songhai [1 ]
机构：
[1] Univ Iowa, Iowa City, IA USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-4683
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4683
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Genomics of HER2+breast cancer
    Perou, C.
    CANCER RESEARCH, 2022, 82 (04)
  • [42] The role of neoadjuvant HER2-targeted therapies in HER2-overexpressing breast cancers
    Lemieux, J.
    Clemons, M.
    Provencher, L.
    Dent, S.
    Latreille, J.
    Mackey, J.
    Pritchard, K. I.
    Rayson, D.
    Verma, Sh.
    Verma, Su.
    Wang, B.
    Chia, S.
    CURRENT ONCOLOGY, 2009, 16 (05) : 316 - 325
  • [43] A HER3/DUSP6 loop determines sensitivity to HER2-targeted therapies in breast cancer
    Momeny, M.
    Merisaari, J.
    Padzik, A.
    Tienhaara, M.
    Aspelin, W.
    Westermarck, J.
    ANNALS OF ONCOLOGY, 2020, 31 : S1093 - S1093
  • [44] GLI2 inhibition suppresses metastasis of HER2+breast cancer
    Gupta, Parul
    Ranjan, Alok
    Fofaria, Neel M.
    Srivastava, Sanjay K.
    CANCER RESEARCH, 2015, 75
  • [45] Pre-clinical study of amcenestrant and HER2-targeted therapies in HER2+/ER+ breast cancer cell line models
    Mahdi, Amira F.
    Ashfield, Niall
    Conlon, Neil T.
    Crown, John
    Collins, Denis M.
    CANCER RESEARCH, 2023, 83 (05)
  • [46] The benefit of HER2-targeted therapies on overall survival of patients with metastatic HER2-positive breast cancer – a systematic review
    Diogo Mendes
    Carlos Alves
    Noémia Afonso
    Fátima Cardoso
    José Luís Passos-Coelho
    Luís Costa
    Sofia Andrade
    Francisco Batel-Marques
    Breast Cancer Research, 17
  • [47] The benefit of HER2-targeted therapies on overall survival of patients with metastatic HER2-positive breast cancer - a systematic review
    Mendes, Diogo
    Alves, Carlos
    Afonso, Noemia
    Cardoso, Fatima
    Passos-Coelho, Jose Luis
    Costa, Luis
    Andrade, Sofia
    Batel-Marques, Francisco
    BREAST CANCER RESEARCH, 2015, 17
  • [48] Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer
    Zuo, Wen-Jia
    Jiang, Yi-Zhou
    Wang, Yu-Jie
    Xu, Xiao-En
    Hu, Xin
    Liu, Guang-Yu
    Wu, Jiong
    Di, Gen-Hong
    Yu, Ke-Da
    Shao, Zhi-Ming
    CLINICAL CANCER RESEARCH, 2016, 22 (19) : 4859 - 4869
  • [49] The Effect of HER2 Amplification in HER2+Breast Cancer
    Lee, M. K.
    Hurvitz, S. A.
    Tran, B. N.
    Fu, Y.
    Chung, D. U.
    Gornbein, J.
    Apple, S. K.
    Chang, H. R.
    ANNALS OF SURGICAL ONCOLOGY, 2015, 22 : S45 - S45
  • [50] Role of Fcγ receptors in HER2-targeted breast cancer therapy
    Musolino, Antonino
    Gradishar, William J.
    Rugo, Hope S.
    Nordstrom, Jeffrey L.
    Rock, Edwin P.
    Arnaldez, Fernanda
    Pegram, Mark D.
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (01)
12345