Inhibition of PKC beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy

被引：0
|
作者：
Connelly, Kim A.
Kelly, Darren A.
Zhang, Yuan
Prior, David L.
Krum, Henry
Gilbert, Richard E.
机构：
[1] Univ Melbourne, St Vincents Hosp, Dept Med, Fitzroy, Vic 3065, Australia
[2] St Vincents Hosp, Cardiac Invest Unit, Fitzroy, Vic 3065, Australia
[3] Monash Univ, Fac Med Nursing & Hlth Sci, Dept Epidemiol & Prevent Med, NHMRC CCRE Therapeut, Melbourne, Vic, Australia
[4] Monash Univ, Fac Med Nursing & Hlth Sci, Dept Med, NHMRC CCRE Therapeut, Melbourne, Vic, Australia
[5] St Michaels Hosp, Dept Med, Toronto, ON M5B 1W8, Canada
来源：
CIRCULATION | 2006年 / 114卷 / 18期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：843 / 843
页数：1
相关论文
共 44 条
  • [21] Inhibition Of Histone Deacetylase Activity Represses Matrix Metalloproteinase-9 Induction And Preserves Cardiac Function Post Myocardial Infarction
    Mani, Santhosh
    Kern, Christine B.
    Addy, Benjamin
    Kasiganesan, Harinath
    Rivers, William T.
    Plyler, Rebecca A.
    Spinale, Francis G.
    Mukherjee, Rupak
    Menick, Donald R.
    CIRCULATION, 2008, 118 (18) : S498 - S498
  • [22] Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis
    Conway, Bryan R.
    Betz, Boris
    Sheldrake, Tara A.
    Manning, Jonathan R.
    Dunbar, Donald R.
    Dobyns, Abigail
    Hughes, Jeremy
    Mullins, John J.
    NEPHROLOGY, 2014, 19 (12) : 802 - 813
  • [23] Inhibition of inducible nitric oxide synthase and superoxide production reduces matrix metalloproteinase-9 activity and restores coronary vasomotor function in rat cardiac allografts
    Egi, K
    Conrad, NE
    Kwan, J
    Schulze, C
    Schulz, R
    Wildhirt, SM
    EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2004, 26 (02) : 262 - 269
  • [24] Intramyocardial gene therapy with adeno beta-catenin preserves cardiac function by increased angiogenesis and cell survival in type I diabetic rat
    Suresh, Sumanth Channapatna
    Thirunavukkarasu, Mahesh
    Selvaraju, Vaithinathan
    Maulik, Nilanjana
    Sanchez, Juan A.
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2012, 215 (03) : S33 - S33
  • [25] Inhibition of matrix metalloproteinase (MMP) activity in mice reduces LV remodeling and depresses cardiac function after myocardial infarction
    Creemers, EEJM
    Cleutjens, JPM
    Smits, JFM
    Daemen, MJAP
    CIRCULATION, 1999, 100 (18) : 250 - 250
  • [26] Inhibition of TGF-beta pathway reverts extracellular matrix remodeling in T. cruzi-infected cardiac microtissues
    Ferrao, P. Mello
    Waghabi, M. C.
    Garzoni, L. R.
    CARDIOVASCULAR RESEARCH, 2012, 93 : S41 - S41
  • [27] Selective inhibition of the NLRP3 inflammasome dose-dependently reduces infarct size and preserves cardiac function in a porcine model of myocardial infarction
    Van Hout, G. P. J.
    Bosch, L.
    Ellenbroek, G. H. J. M.
    Cooper, M.
    Van Solinge, W. W.
    De Jager, S. C. A.
    Robertson, A.
    Pasterkamp, G.
    Hoefer, I. E.
    EUROPEAN HEART JOURNAL, 2015, 36 : 679 - 679
  • [28] Extracellular Matrix Components Isolated From Diabetic Mice Alters Cardiac Fibroblast Function Through the AGE/RAGE Signaling Cascade
    Burr, Stephanie
    Stewart, James A.
    CIRCULATION RESEARCH, 2019, 125
  • [29] Extracellular matrix components isolated from diabetic mice alters cardiac fibroblast function through the AGE/RAGE signaling cascade
    Burr, Stephanie
    Stewart, James A.
    FASEB JOURNAL, 2019, 33
  • [30] Extracellular matrix components isolated from diabetic mice alter cardiac fibroblast function through the AGE/RAGE signaling cascade
    Burr, Stephanie D.
    Stewart, James A., Jr.
    LIFE SCIENCES, 2020, 250
12345