DESIGN, SYNTHESIS AND CHARACTERIZATION OF NOVEL SERIES OF 1,3-THIAZOLE CONTAINING HETEROCYCLES AS INHIBITORS OF DHFR FOR USE AS ANTICANCER AGENTS

被引:0
|
作者
Pawar, Sunil Dilip [1 ]
Mithila, N. S. [1 ]
Yadav, Abhishek [1 ]
Bhat, Shraddha [1 ]
Varghese, Roshni [1 ]
Sharma, Anjali [1 ]
Somayaji, Sharvari [1 ]
Sanjukta, G. P. [1 ]
Vibha, S. [1 ]
Agarwal, Anil Kumar [1 ]
机构
[1] CHRIST Deemed Univ, Dept Chem, Bengaluru, India
关键词
D O I
暂无
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:99 / 102
页数:4
相关论文
共 50 条
  • [21] Synthesis, antitumor activity and mechanism of action of novel 1,3-thiazole derivatives containing hydrazide-hydrazone and carboxamide moiety
    He, Haifeng
    Wang, Xiaoyan
    Shi, Liqiao
    Yin, Wenyan
    Yang, Ziwen
    He, Hongwu
    Liang, Ying
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (14) : 3263 - 3270
  • [22] Design, synthesis, characterization, docking studies of novel 4-phenyl acrylamide-1,3-thiazole derivatives as anti-inflammatory and anti-ulcer agents
    Pallavi, H. M.
    Al-Ostoot, Fares Hezam
    Kameshwar, Vivek Hamse
    Khamees, Hussein
    Khanum, Shaukath Ara
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1292
  • [23] Synthesis and Biological Evaluation of Some Novel Thiazole-Based Heterocycles as Potential Anticancer and Antimicrobial Agents
    Abu-Melha, Sraa
    Edrees, Mastoura M.
    Salem, Heba H.
    Kheder, Nabila A.
    Gomha, Sobhi M.
    Abdelaziz, Mohamad R.
    MOLECULES, 2019, 24 (03)
  • [24] Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors
    Wang, Guangcheng
    Liu, Wenjing
    Fan, Meiyan
    He, Min
    Li, Yongjun
    Peng, Zhiyun
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021, 36 (01) : 1694 - 1702
  • [25] Synthesis of novel substituted 4,4′-(1,4-phenylene)bis(1,3-thiazole)s
    Manju, Sreedharan L.
    Asha, Sarojini
    Reji, Thankappan F. A. F.
    Rajasekharan, Kallikat N.
    ARKIVOC, 2008, : 288 - 296
  • [26] Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties
    Sayed, Eman M.
    Bakhite, Etify A.
    Hassanien, Reda
    Farhan, Nasser
    Aly, Hanan F.
    Morsy, Salma G.
    Hassan, Nivin A.
    BMC CHEMISTRY, 2024, 18 (01)
  • [27] Novel tetrahydroisoquinolines as DHFR and CDK2 inhibitors: synthesis, characterization, anticancer activity and antioxidant properties
    Eman M. Sayed
    Etify A. Bakhite
    Reda Hassanien
    Nasser Farhan
    Hanan F. Aly
    Salma G. Morsy
    Nivin A. Hassan
    BMC Chemistry, 18
  • [28] Synthesis and activity of (+)-usnic acid and (-)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis
    Bekker, Olga B.
    Sokolov, Dmitry N.
    Luzina, Olga A.
    Komarova, Nina I.
    Gatilov, Yuriy V.
    Andreevskaya, Sofia N.
    Smirnova, Tatiana G.
    Maslov, Dmitry A.
    Chernousova, Larisa N.
    Salakhutdinov, Nariman F.
    Danilenko, Valery. N.
    MEDICINAL CHEMISTRY RESEARCH, 2015, 24 (07) : 2926 - 2938
  • [29] The design, synthesis, and in vitro trypanocidal and leishmanicidal activities of 1,3-thiazole and 4-thiazolidinone ester derivatives
    Haroon, Muhammad
    de Barros Dias, Mabilly Cox Holanda
    Santos, Aline Caroline da Silva
    Pereira, Valeria Rego Alves
    Barros Freitas, Luiz Alberto
    Balbinot, Rodolfo Bento
    Kaplum, Vanessa
    Nakamura, Celso Vataru
    Alves, Luiz Carlos
    Brayner, Fabio Andre
    Leite, Ana Cristina Lima
    Akhtar, Tashfeen
    RSC ADVANCES, 2021, 11 (04) : 2487 - 2500
  • [30] Synthesis and activity of (+)-usnic acid and (−)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis
    Olga B. Bekker
    Dmitry N. Sokolov
    Olga A. Luzina
    Nina I. Komarova
    Yuriy V. Gatilov
    Sofia N. Andreevskaya
    Tatiana G. Smirnova
    Dmitry A. Maslov
    Larisa N. Chernousova
    Nariman F. Salakhutdinov
    Valery. N. Danilenko
    Medicinal Chemistry Research, 2015, 24 : 2926 - 2938