Structure-based discovery and optimization of inhibitors for the class D β-lactamase OXA-24/40

被引：0
|
作者：
Powers, Rachel
Mitchell, Joshua
Basinski, Brian
Uyen Pham
机构：
来源：
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES | 2018年 / 74卷
关键词：
D O I：
10.1107/S010876731809606X
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：A394 / A394
页数：1
相关论文
共 50 条
  • [31] Structure-based discovery of CFTR potentiators and inhibitors
    Liu, Fangyu
    Kaplan, Anat Levit
    Levring, Jesper
    Einsiedel, Jurgen
    Tiedt, Stephanie
    Distler, Katharina
    Omattage, Natalie S.
    Kondratov, Ivan S.
    Moroz, Yurii S.
    Pietz, Harlan L.
    Irwin, John J.
    Gmeiner, Peter
    Shoichet, Brian K.
    Chen, Jue
    CELL, 2024, 187 (14) : 3712 - 3725.e34
  • [32] Structure-based optimization of PKCθ inhibitors
    Mosyak, L.
    Xu, Z.
    Joseph-McCarthy, D.
    Brooijmans, N.
    Somers, W.
    Chaudhary, D.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 : 1027 - 1031
  • [33] Structure-based optimization of MurF inhibitors
    Stamper, GF
    Longenecker, KL
    Fry, EH
    Jakob, CG
    Florjancic, AS
    Gu, YG
    Anderson, DD
    Cooper, CS
    Zhang, T
    Clark, RF
    Cia, Y
    Black-Schaefer, CL
    McCall, JO
    Lerner, CG
    Hajduk, PJ
    Beutel, BA
    Stoll, VS
    CHEMICAL BIOLOGY & DRUG DESIGN, 2006, 67 (01) : 58 - 65
  • [34] Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii
    Introvigne, Maria Luisa
    Beardsley, Trevor J. J.
    Fernando, Micah C. C.
    Leonard, David A. A.
    Wallar, Bradley J. J.
    Rudin, Susan D. D.
    Taracila, Magdalena A. A.
    Rather, Philip N. N.
    Colquhoun, Jennifer M. M.
    Song, Shaina
    Fini, Francesco
    Hujer, Kristine M. M.
    Hujer, Andrea M. M.
    Prati, Fabio
    Powers, Rachel A. A.
    Bonomo, Robert A. A.
    Caselli, Emilia
    ANTIBIOTICS-BASEL, 2023, 12 (04):
  • [35] Structure of the class D β-lactamase OXA-29, a different carbonated dimer
    Kerff, F.
    Herman, R.
    Sauvage, E.
    Galleni, M.
    Charlier, P.
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2006, 62 : S151 - S151
  • [36] Structure-based optimization of non-peptidic Cathepsin D inhibitors
    Graedler, Ulrich
    Czodrowski, Paul
    Tsaklakidis, Christos
    Klein, Markus
    Werkmann, Daniela
    Lindemann, Sven
    Maskos, Klaus
    Leuthner, Birgitta
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (17) : 4141 - 4150
  • [37] MM-GBSA and QM/MM simulation-based in silico approaches for the inhibition of Acinetobacter baumannii class D OXA-24 β-lactamase using antimicrobial peptides melittin and RP-1
    Mandal, Manisha
    Mandal, Shyamapada
    CHEMICAL PHYSICS IMPACT, 2024, 8
  • [38] Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A β-Lactamase
    Nichols, Derek A.
    Jaishankar, Priyadarshini
    Larson, Wayne
    Smith, Emmanuel
    Liu, Guoqing
    Beyrouthy, Racha
    Bonnet, Richard
    Renslo, Adam R.
    Chen, Yu
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (05) : 2163 - 2172
  • [39] Discovery of Novel Neuraminidase Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay
    Yu, Rao
    Cheng, Li Ping
    Li, Meng
    Pang, Wan
    ACS MEDICINAL CHEMISTRY LETTERS, 2019, 10 (12): : 1667 - 1673
  • [40] Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthase
    Tondi, D
    Slomczynska, U
    Costi, MR
    Watterson, DM
    Ghelli, S
    Shoichet, BK
    CHEMISTRY & BIOLOGY, 1999, 6 (05): : 319 - 331
12345