Two New Natural Products from Portulaca oleracea L. and their Antioxidant and Antiacetylcholinesterase Activities

被引:0
|
作者
Xu, Haoran [1 ]
Zhang, Wenjie [1 ]
Leng, Aijing [2 ]
Ying, Xixiang [1 ]
机构
[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China
[2] Dalian Med Univ, Affiliated Hosp 1, Dept Pharm, Dalian, Peoples R China
来源
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 03期
基金
中国国家自然科学基金;
关键词
antiacetylcholinesterase activity; antioxidant activity; Portulaca oleracea L; two new natural products; ALZHEIMERS-DISEASE; ALKALOIDS; INHIBITORS; PLANTS;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Two new natural products already known from synthesis, benzoic acid, 4-[[(2-hydroxyethyl)amino]carbonyl]-methyl ester (1) and benzoic acid, 3-[[(2-hydroxyethyl)amino]carbonyl]-methyl ester (2) were isolated from Portulaca oleracea L. for the first time and their structures were identified using spectroscopic methods including (HNMR)-H-1, (CNMR)-C-13 and HR-ESI(+)-TOF-MS. Both compounds presented antioxidant activity with IC50 of 56.49 and 54.89 mu g/mL and antiacetylcholinesterase activitywith IC50 of 28.95 and 24.38 mu g/mL, respectively.
引用
收藏
页码:480 / 483
页数:4
相关论文
共 50 条
  • [21] Two Novel Triterpenoids from Portulaca oleracea L.
    Xin, Hai-Liang
    Xu, Yan-Feng
    Hou, Yin-Huan
    Zhang, Ya-Ni
    Yue, Xiao-Qiang
    Lu, Jin-Cai
    Ling, Chang-Quan
    HELVETICA CHIMICA ACTA, 2008, 91 (11) : 2075 - 2080
  • [22] Antioxidant activities of aqueous extracts of purslane (Portulaca oleracea subsp sativa L.)
    Peksel, A.
    Arisan-Atac, I.
    Yanardag, R.
    ITALIAN JOURNAL OF FOOD SCIENCE, 2006, 18 (03) : 295 - 308
  • [23] Seven compounds from Portulaca oleracea L. and their anticholinesterase activities
    Xu, Wen
    Wang, Jianhua
    Ju, Baozhao
    Lan, Xiujuan
    Ying, Xixiang
    Stien, Didier
    NATURAL PRODUCT RESEARCH, 2022, 36 (10) : 2547 - 2553
  • [24] Portulene, a new diterpene from Portulaca oleracea L.
    Elkhayat, Ehab S.
    Ibrahim, Sabrin R. M.
    Aziz, Mohamed A.
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2008, 10 (11) : 1039 - 1043
  • [25] A New Tricyclic Alkaloid from Portulaca oleracea L.
    Yue, Su
    Jiao, Ze-Zhao
    Sun, Hong-Xiang
    Jin, Tian-Yun
    Xiang, Lan
    HELVETICA CHIMICA ACTA, 2015, 98 (07) : 961 - 966
  • [26] A new alkaloid and two organic acids from Portulaca oleracea L. and their bioactivities
    Liu, Peishan
    Lan, Xiujuan
    Tao, Xiaojun
    Tian, Jiayin
    Ying, Xixiang
    Stien, Didier
    NATURAL PRODUCT RESEARCH, 2024, 38 (01) : 68 - 77
  • [27] Two new esters from the aerial parts of Portulaca oleracea L. and their bioactivities
    Gu, Yingying
    Ying, Zheming
    Lan, Xiujuan
    Ying, Xixiang
    Yang, Guanlin
    PHYTOCHEMISTRY LETTERS, 2021, 44 : 98 - 101
  • [28] Two new alkaloids from Portulaca oleracea and their cytotoxic activities
    Tian, Jin-Long
    Liang, Xiao
    Gao, Pin-Yi
    Li, Dan-Qi
    Sun, Qian
    Li, Ling-Zhi
    Song, Shao-Jiang
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 16 (03) : 259 - 264
  • [29] Alkaloids from Portulaca oleracea L.
    Xiang, L
    Xing, DM
    Wang, W
    Wang, RF
    Ding, Y
    Du, LJ
    PHYTOCHEMISTRY, 2005, 66 (21) : 2595 - 2601
  • [30] Antioxidant activities of novel small-molecule polysaccharide fractions purified from Portulaca oleracea L.
    Yu-Ping Li
    Li-Hua Yao
    Guan-Jie Wu
    Xiao-Fang Pi
    Yan-Chun Gong
    Ruo-Shong Ye
    Chen-Xi Wang
    Food Science and Biotechnology, 2014, 23 : 2045 - 2052