YM-32890 A and B, new types of macrolide antibiotics produced by Cytophaga sp.

被引:2
|
作者
Kamigiri, K
Tokunaga, T
Sugawara, T
Nagai, K
Shibazaki, M
Setiawan, B
Rantiatmodjo, RM
Morioka, M
Suzuki, K
机构
[1] YAMANOUCHI PHARMACEUT CO LTD,MOL CHEM RES LAB,TSUKUBA,IBARAKI 305,JAPAN
[2] PT KALBE FARMA,JAKARTA 10002,INDONESIA
来源
JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 07期
关键词
D O I
10.7164/antibiotics.50.556
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Two new types of macrolide antibiotics, YM-32890 A. and B, have been isolated from the fermentation broth of Cytophaga sp. YL-O2905S. In this paper, the taxonomy of the producing strain, Fermentation, isolation, structure elucidation, and biological activity of the antibiotics are reported. YM-32890 A inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast.
引用
收藏
页码:556 / 561
页数:6
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