YM-32890 A and B, new types of macrolide antibiotics produced by Cytophaga sp.

被引：2

作者：

Kamigiri, K

Tokunaga, T

Sugawara, T

Nagai, K

Shibazaki, M

Setiawan, B

Rantiatmodjo, RM

Morioka, M

Suzuki, K

机构：

[1] YAMANOUCHI PHARMACEUT CO LTD,MOL CHEM RES LAB,TSUKUBA,IBARAKI 305,JAPAN

[2] PT KALBE FARMA,JAKARTA 10002,INDONESIA

来源：

JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 07期

关键词：

D O I：

10.7164/antibiotics.50.556

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two new types of macrolide antibiotics, YM-32890 A. and B, have been isolated from the fermentation broth of Cytophaga sp. YL-O2905S. In this paper, the taxonomy of the producing strain, Fermentation, isolation, structure elucidation, and biological activity of the antibiotics are reported. YM-32890 A inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast.

引用

页码：556 / 561

页数：6

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