Prediction of tumor heterogeneity in localized prostate cancer

被引：6

作者：

Huland, H

Graefen, M

Haese, A

Hammerer, PG

Palisaar, J

Pichlmeier, U

Henke, RP

Erbersdobler, A

Huland, E

Lilja, H

机构：

[1] Univ Clin Hamburg, Hosp Eppendorf, Dept Urol, D-20246 Hamburg, Germany

[2] Univ Clin Hamburg, Hosp Eppendorf, Dept Biostat, D-20246 Hamburg, Germany

[3] Univ Clin Hamburg, Hosp Eppendorf, Inst Pathol, D-20246 Hamburg, Germany

[4] Lund Univ, Dept Clin Chem, S-20502 Malmo, Sweden

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2002年 / 29卷 / 01期

关键词：

D O I：

10.1016/S0094-0143(02)00006-X

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical T1-T2 prostatic carcinoma is a heterogeneous tumor in respect to pathologic stage and outcome. Tumor heterogeneity can be fairly good predicted by the use of classification and regression tree analysis with preoperative parameters, especially a quantitative analysis of Gleason grade 4-5 cancer in six systematic biopsies and a determination of preoperative prostate-specific antigen levels, to predict lymph node status, capsular penetration, and outcome.

引用

页码：213 / +

页数：11

共 50 条

[41] Prostate brachytherapy for localized prostate cancer
Ciezki J.P.
Current Treatment Options in Oncology, 2005, 6 (5) : 389 - 393
[42] Epigenetic mechanisms underlying subtype heterogeneity and tumor recurrence in prostate cancer
Goutam Chakraborty
Kasmira Gupta
Natasha Kyprianou
Nature Communications, 14
[43] TUMOR HETEROGENEITY AND DRUG SENSITIVITY MODELLED IN PRIMARY PROSTATE CANCER ORGANOIDS
Kang, Juening
Karkampouna, Sofia
Ovchinnikova, Katja
Chouvardas, Panagiotis
Kruithof-de Julio, Marianna
Thalmann, George
JOURNAL OF UROLOGY, 2023, 209 : E125 - E125
[44] Are Elderly Patients With Clinically Localized Prostate Cancer Overtreated? Exploring Heterogeneity in Survival Effects
Basu, Anirban
Gore, John L.
MEDICAL CARE, 2015, 53 (01) : 79 - 86
[45] Characterization of the molecular heterogeneity of circulating tumor cells in metastatic prostate cancer
Massard, Christophe
Oulhen, Marianne
Valent, Alexander
Lemoulec, Sylvestre
Fizazi, Karim
Vielh, Philippe
Farace, Francoise
CANCER RESEARCH, 2014, 74 (19)
[46] Molecular heterogeneity in diverse prostate cancer circulating tumor cell subsets
Sperger, Jamie M.
Heninger, Erika
Schehr, Jennifer L.
Allen, Haley E. F.
Singh, Anupama
Lang, Joshua M.
CANCER RESEARCH, 2016, 76
[47] Epigenetic mechanisms underlying subtype heterogeneity and tumor recurrence in prostate cancer
Chakraborty, Goutam
Gupta, Kasmira
Kyprianou, Natasha
NATURE COMMUNICATIONS, 2023, 14 (01)
[48] Transcriptome sequencing in prostate cancer identifies inter-tumor heterogeneity
Mendonca, Janet
Sharma, Anup
Kachhap, Sushant
ASIAN JOURNAL OF ANDROLOGY, 2015, 17 (03) : 435 - 436
[49] Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer
Wyatt, Alexander W.
Mo, Fan
Wang, Kendric
McConeghy, Brian
Brahmbhatt, Sonal
Jong, Lina
Mitchell, Devon M.
Johnston, Rebecca L.
Haegert, Anne
Li, Estelle
Liew, Janet
Yeung, Jake
Shrestha, Raunak
Lapuk, Anna V.
McPherson, Andrew
Shukin, Robert
Bell, Robert H.
Anderson, Shawn
Bishop, Jennifer
Hurtado-Coll, Antonio
Xiao, Hong
Chinnaiyan, Arul M.
Mehra, Rohit
Lin, Dong
Wang, Yuzhuo
Fazli, Ladan
Gleave, Martin E.
Volik, Stanislav V.
Collins, Colin C.
GENOME BIOLOGY, 2014, 15 (08): : 426
[50] Interrogating cell heterogeneity and dormancy in prostate cancer disseminated tumor cells
Ruppender, Nazanin S.
Brown, Lisha
Coleman, Roger
Lakely, Bryce
Coleman, Ilsa
Welty, Christopher
Gulati, Roman
Nelson, Peter S.
Lange, Paul H.
Corey, Eva
Vessella, Robert
Morrissey, Colm
CANCER RESEARCH, 2012, 72

← 1 2 3 4 5 →