Prediction of tumor heterogeneity in localized prostate cancer

被引:6
|
作者
Huland, H
Graefen, M
Haese, A
Hammerer, PG
Palisaar, J
Pichlmeier, U
Henke, RP
Erbersdobler, A
Huland, E
Lilja, H
机构
[1] Univ Clin Hamburg, Hosp Eppendorf, Dept Urol, D-20246 Hamburg, Germany
[2] Univ Clin Hamburg, Hosp Eppendorf, Dept Biostat, D-20246 Hamburg, Germany
[3] Univ Clin Hamburg, Hosp Eppendorf, Inst Pathol, D-20246 Hamburg, Germany
[4] Lund Univ, Dept Clin Chem, S-20502 Malmo, Sweden
关键词
D O I
10.1016/S0094-0143(02)00006-X
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The clinical T1-T2 prostatic carcinoma is a heterogeneous tumor in respect to pathologic stage and outcome. Tumor heterogeneity can be fairly good predicted by the use of classification and regression tree analysis with preoperative parameters, especially a quantitative analysis of Gleason grade 4-5 cancer in six systematic biopsies and a determination of preoperative prostate-specific antigen levels, to predict lymph node status, capsular penetration, and outcome.
引用
收藏
页码:213 / +
页数:11
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