Outbreak of mumps in a vaccinated child population: a question of vaccine failure?

被引：90

作者：

Vandermeulen, C

Roelants, M

Vermoere, M

Roseeuw, K

Goubau, P

Hoppenbrouwers, K

机构：

[1] Katholieke Univ Leuven, Dept Youth Hlth Care, B-3000 Louvain, Belgium

[2] Pupil Guidance Ctr Brugge, B-8000 Brugge, Belgium

[3] Catholic Univ Louvain, Lab Reference Sida, B-1200 Brussels, Belgium

来源：

VACCINE | 2004年 / 22卷 / 21-22期

关键词：

outbreak; mumps; vaccination;

D O I：

10.1016/j.vaccine.2004.02.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In Belgium, children are immunized against measles-mumps-rubella (MMR) in a two-dose schedule at the age of 15 months and I I years. Despite these recommendations, epidemics of mumps still occur. During an outbreak of mumps in Bruges (Belgium), 105 cases were registered in seven schools (age group 3-12 years). Lower than optimal vaccination coverage, inadequate vaccination schedule and a combination of primary and/or secondary vaccine failure are considered as possible reasons for the outbreak as described in the article. The role of secondary vaccine failure is highlighted. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2713 / 2716

页数：4

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