Anterior Uveitis Complicating Zoledronic Acid Infusion

被引:26
|
作者
Colucci, Annalisa [1 ]
Modorati, Giulio [1 ]
Miserocchi, Elisabetta [1 ]
Di Matteo, Federico [1 ]
Rama, Paolo [1 ]
机构
[1] Ist Sci San Raffaele, I-20132 Milan, Italy
关键词
bisphosphonates; breast cancer; uveitis; zoledronate; CANCER;
D O I
10.1080/09273940902916111
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Zoledronic acid is the most effective treatment in patients with hypercalcemia secondary to malignancy; occasionally it can be related to ocular inflammation. We report a case of severe unilateral anterior uveitis following administration of intravenous zoledronic acid in a patient with frontal hyperostosis secondary to breast cancer. The patient developed anterior uveitis 24 hours after the administration of intravenous zoledronate. The patient was treated with topical prednisone and cycloplegic eye drops, with complete recovery after one month. This report shows that, on rare occasions, zoledronic acid can be a possible cause of acute anterior uveitis.
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页码:267 / 268
页数:2
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