Targeted memory reactivation of newly learned words during sleep triggers REM-mediated integration of new memories and existing knowledge

被引：39
|
作者：
Tamminen, Jakke [1 ,2 ]
Ralph, Matthew A. Lambon [1 ]
Lewis, Penelope A. [1 ]
机构：
[1] Univ Manchester, Sch Psychol Sci, Neurosci & Aphasia Res Unit, Manchester M13 9PL, Lancs, England
[2] Royal Holloway Univ London, Dept Psychol, Egham TW20 0EX, Surrey, England
来源：
NEUROBIOLOGY OF LEARNING AND MEMORY | 2017年 / 137卷
基金：
英国生物技术与生命科学研究理事会; 英国经济与社会研究理事会;
关键词：
Memory; Sleep; Memory consolidation; Targeted memory reactivation; HIPPOCAMPAL RIPPLES; SPINDLE ACTIVITY; ENHANCEMENT; NEOCORTEX;
D O I：
10.1016/j.nlm.2016.11.012
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
Recent memories are spontaneously reactivated during sleep, leading to their gradual strengthening. Whether reactivation also mediates the integration of new memories with existing knowledge is unknown. We used targeted memory reactivation (TMR) during slow-wave sleep (SWS) to selectively cue reactivation of newly learned spoken words. While integration of new words into their phonological neighbourhood was observed in both cued and uncued words after sleep, TMR-triggered integration was predicted by the time spent in rapid eye movement (REM) sleep. These data support complementary roles for SWS and REM in memory consolidation. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码：77 / 82
页数：6
相关论文
共 15 条
  • [1] Reactivating newly learnt words during slow wave sleep triggers REM-mediated integration of new memories and existing knowledge
    Tamminen, J.
    Ralph, M. Lambon
    Lewis, P.
    JOURNAL OF SLEEP RESEARCH, 2012, 21 : 253 - 254
  • [2] Losing memories during sleep after targeted memory reactivation
    Simon, Katharine C. N. S.
    Gomez, Rebecca L.
    Nadel, Lynn
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2018, 151 : 10 - 17
  • [3] Does targeted memory reactivation during NREM sleep require complementary REM sleep for memory consolidation?
    Ortega, R. Sifuentes
    Peigneux, P.
    JOURNAL OF SLEEP RESEARCH, 2022, 31
  • [4] Targeted Memory Reactivation During REM Sleep in Patients With Social Anxiety Disorder
    Borghese, Francesca
    Henckaerts, Pauline
    Guy, Fanny
    Perez Mayo, Coral
    Delplanque, Sylvain
    Schwartz, Sophie
    Perogamvros, Lampros
    FRONTIERS IN PSYCHIATRY, 2022, 13
  • [5] Targeted memory reactivation during sleep can induce forgetting of overlapping memories
    Joensen, Barour H.
    Harrington, Marcus O.
    Berens, Sam C.
    Cairney, Scott A.
    Gaskell, M. Gareth
    Horner, Aidan J.
    LEARNING & MEMORY, 2022, 29 (11) : 401 - 411
  • [6] Sleep Spindle Activity is Associated with the Integration of New Memories and Existing Knowledge
    Tamminen, Jakke
    Payne, Jessica D.
    Stickgold, Robert
    Wamsley, Erin J.
    Gaskell, M. Gareth
    JOURNAL OF NEUROSCIENCE, 2010, 30 (43): : 14356 - 14360
  • [7] TARGETED MEMORY REACTIVATION DURING REM SLEEP: IMPLICATIONS IN THE TREATMENT OF SOCIAL ANXIETY DISORDER
    Borghese, F.
    Henckaerts, P.
    Guy, F.
    Mayo, C.
    Delplanque, S.
    Schwartz, S.
    Perogamvros, L.
    SLEEP MEDICINE, 2022, 100 : S39 - S40
  • [8] Targeted Memory Reactivation during Sleep Adaptively Promotes the Strengthening or Weakening of Overlapping Memories
    Oyarzun, Javiera P.
    Moris, Joaquin
    Luque, David
    de Diego-Balaguer, Ruth
    Fuentemilla, Lluis
    JOURNAL OF NEUROSCIENCE, 2017, 37 (32): : 7748 - 7758
  • [9] THE EFFECT OF NOCTURNAL SLEEP MANIPULATIONS ON THE ACCESSIBILITY AND FIDELITY OF NEWLY-ACQUIRED MEMORIES: TARGETED MEMORY REACTIVATION
    MacDonald, K.
    Cote, K.
    SLEEP MEDICINE, 2019, 64 : S236 - S236
  • [10] Emotional arousal modulates oscillatory correlates of targeted memory reactivation during NREM, but not REM sleep
    Mick Lehmann
    Thomas Schreiner
    Erich Seifritz
    Björn Rasch
    Scientific Reports, 6
12