PHD3-mediated prolyl hydroxylation of non-muscle actin impairs polymerization and cell motility

被引:0
|
作者
Luo, Weibo [1 ]
Semenza, Gregg L. [2 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA
[2] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
关键词
D O I
10.1158/1538-7445.AM2015-525
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
525
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Inhibition of PHD3 by salidroside promotes neovascularization through cell-cell communications mediated by muscle-secreted angiogenic factors
    Zhang, Jing
    Kasim, Vivi
    Xie, Yu-Dan
    Huang, Can
    Sisjayawan, Julita
    Ariyanti, Agnes Dwi
    Yan, Xue-Song
    Wu, Xiao-Yan
    Liu, Cai-Ping
    Yang, Li
    Miyagishi, Makoto
    Wu, Shou-Rong
    SCIENTIFIC REPORTS, 2017, 7
  • [32] Non-muscle tropomyosin (Tpm3) is crucial for asymmetric cell division and maintenance of cortical integrity in mouse oocytes
    Jang, Woo-In
    Jo, Yu-Jin
    Kim, Hak-Cheol
    Jia, Jia-Lin
    Namgoong, Suk
    Kim, Nam-Hyung
    CELL CYCLE, 2014, 13 (15) : 2359 - 2369
  • [33] Differential Roles of Non-Muscle Myosin Isoforms in Traction Force Development and 3D Breast Cancer Cell Invasion
    Thomas, D. G.
    Denais, C. M.
    Lammerding, J.
    Baskaran, H.
    Egelhoff, T. T.
    MOLECULAR BIOLOGY OF THE CELL, 2013, 24
  • [34] Broadening the Spectrum of Actin-Based Protrusive Activity Mediated by Arp2/3 Complex-Facilitated Polymerization: Motility of Cytoplasmic Ridges and Tubular Projections
    Henson, John H.
    Gianakas, Anastasia D.
    Henson, Lauren H.
    Lakin, Christina L.
    Voss, Meagen K.
    Bewersdorf, Joerg
    Oldenbourg, Rudolf
    Morris, Robert L.
    CYTOSKELETON, 2014, 71 (08) : 484 - 500
  • [35] Gene Expression Levels of the Prolyl Hydroxylase Domain Proteins PHD1 and PHD2 but Not PHD3 Are Decreased in Primary Tumours and Correlate with Poor Prognosis of Patients with Surgically Resected Non-Small-Cell Lung Cancer
    Koren, Ana
    Rijavec, Matija
    Krumpestar, Tomaz
    Kern, Izidor
    Sadikov, Aleksander
    Cufer, Tanja
    Korosec, Peter
    CANCERS, 2021, 13 (10)
  • [36] Hematopoietic cell specific protein HS1 promotes the Arp2/3 complex-mediated actin polymerization
    Uruno, T
    Zhang, P
    Hao, J
    Liu, J
    Smith, NC
    Zhan, X
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 313A - 313A
  • [37] Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation
    Malek, Natalia
    Mrowczynska, Ewa
    Michrowska, Aleksandra
    Mazurkiewicz, Ewa
    Pavlyk, Iuliia
    Mazur, Antonina Joanna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (08)
  • [38] 14-3-3 proteins tune non-muscle myosin II assembly, providing a possible bridge between cell mechanics and cancer metastasis
    West-Foyle, H.
    Osborne, J.
    Robinson, D.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [39] PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization
    Li, Meng-Yen
    Peng, Wen-Hsin
    Wu, Chien-Hsun
    Chang, Ya-Min
    Lin, Yu-Ling
    Chang, Geen-Dong
    Wu, Han-Chung
    Chen, Guang-Chao
    ONCOGENE, 2019, 38 (44) : 7002 - 7016
  • [40] PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization
    Meng-Yen Li
    Wen-Hsin Peng
    Chien-Hsun Wu
    Ya-Min Chang
    Yu-Ling Lin
    Geen-Dong Chang
    Han-Chung Wu
    Guang-Chao Chen
    Oncogene, 2019, 38 : 7002 - 7016