A practical one-pot synthesis of trans-4,5-disubstituted 2-pyrrolidinones and the related pyrrolidines

被引：10
|
作者：
Yee, NK
机构：
[1] Department of Chemical Development, Boehringer Ingelheim Pharmaceut. I., Ridgefield, CT 06877-0368
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 29期
关键词：
D O I：
10.1016/S0040-4039(97)01134-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A practical and general method for the stereoselective synthesis of trans-4,5-disubstituted 2-pyrrolidinones was developed. Hydride reduction of these pyrrolidinones gave the corresponding pyrrolidines. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：5091 / 5094
页数：4
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