Weight loss;
Energy restriction;
Body composition;
Energy expenditure;
Metabolic rate;
Energy deficit;
Weight maintenance;
Uncoupling proteins;
Mitochondrial efficiency;
MITOCHONDRIAL PROTON LEAK;
BROWN-ADIPOSE-TISSUE;
TERM CALORIE RESTRICTION;
SKELETAL-MUSCLE;
ENERGY-EXPENDITURE;
BODY-COMPOSITION;
UNCOUPLING PROTEIN-3;
ADAPTIVE THERMOGENESIS;
PHYSIOLOGICAL PROFILES;
FEEDBACK SIGNALS;
D O I:
10.1186/1550-2783-11-7
中图分类号:
R15 [营养卫生、食品卫生];
TS201 [基础科学];
学科分类号:
100403 ;
摘要:
Optimized body composition provides a competitive advantage in a variety of sports. Weight reduction is common among athletes aiming to improve their strength-to-mass ratio, locomotive efficiency, or aesthetic appearance. Energy restriction is accompanied by changes in circulating hormones, mitochondrial efficiency, and energy expenditure that serve to minimize the energy deficit, attenuate weight loss, and promote weight regain. The current article reviews the metabolic adaptations observed with weight reduction and provides recommendations for successful weight reduction and long term reduced-weight maintenance in athletes.
机构:
Suny Downstate Med Ctr, Dept Biochem, Brooklyn, NY 11203 USASuny Downstate Med Ctr, Dept Biochem, Brooklyn, NY 11203 USA
Feinman, Richard D.
Fine, Eugene J.
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机构:
Suny Downstate Med Ctr, Dept Biochem, Brooklyn, NY 11203 USA
Jacobi Med Ctr, Dept Nucl Med, Bronx, NY USASuny Downstate Med Ctr, Dept Biochem, Brooklyn, NY 11203 USA
机构:
Harvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Odense Univ Hosp, Dept Endocrinol, Cardiovasc & Metab Prevent Clin, Odense, DenmarkHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Pareek, Manan
Schauer, Philip R.
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机构:
Cleveland Clin, Bariatr & Metab Inst, Cleveland, OH 44106 USAHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Schauer, Philip R.
Kaplan, Lee M.
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机构:
Massachusetts Gen Hosp, Obes Metab & Nutr Inst, Boston, MA 02114 USAHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Kaplan, Lee M.
Leiter, Lawrence A.
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h-index: 0
机构:
Univ Toronto, St Michaels Hosp, Li Ka Shing Knowledge Inst, Toronto, ON, CanadaHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Leiter, Lawrence A.
Rubino, Francesco
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机构:
Kings Coll Hosp London, Diabet & Nutr Sci Div, Dept Metab & Bariatr Surg, London, EnglandHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA
Rubino, Francesco
Bhatt, Deepak L.
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机构:
Harvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USAHarvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA