Clinical Observation of Polycystic Ovary Syndrome Treatment with Resveratrol

被引:0
|
作者
Wang, Fang [1 ]
Zheng, Y. [2 ]
Yuan, Huiqin [1 ]
Dong, Qiyin [3 ]
机构
[1] Huzhou Univ, Affiliated Hosp 1, Dept Gynecol, Huzhou, Peoples R China
[2] Huzhou Univ, Affiliated Hosp 1, Dept Radiol, Huzhou, Peoples R China
[3] Huzhou Matern & Child Care Hosp, Dept Reprod Med, Wuxing 313000, Zhejiang, Peoples R China
关键词
Resveratrol; polycystic ovary syndrome; hyperandrogenemia; hirsutism; insulin; HEALTH; WOMEN;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The fundamental target of the present survey is to explore the clinical impact of resveratrol in treating polycystic ovary syndrome. A number of 104 cases suffering from polycystic ovary syndrome admitted to the hospital from January 2018 to December 2020 were chosen as investigation subjects. The cases were categorized into two groups, namely control and study groups through the random number table technique, with 52 patients in each group. Patients in the group of study were considered to receive 100 % pure resveratrol (once daily, 1000 mg) and cases in the group of control received matched placebo. 3 mo later, the treatment effects of the two groups were scrutinized. Following the treating process, the length of ovary, endometrial thickness and number of sinus follicles in the research group were improved and substantially superior to those in the group of control (all p<0.05). The improvement in menstrual cycle and hair loss in the group of observation was considerably greater than that in the group of control (both p<0.05). Following the treatment, the levels of luteinizing hormone, estradiol and testosterone in the group of observation were less than those in the group of control, with statistically meaningful discrepancies (all p<0.05), but the follicle-stimulating hormone levels had no significant difference. After 3 mo of treating, the expression level of mitofusin-2 in the study group was substantially enhanced in comparison to that in the control group (p<0.05). Resveratrol improved sex hormone levels, menstrual irregularities, hair loss and ovarian function in cases suffering from polycystic ovary syndrome.
引用
收藏
页码:272 / 277
页数:6
相关论文
共 50 条
  • [21] Surgical treatment of polycystic ovary syndrome
    Balen, Adam
    BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 20 (02) : 271 - 280
  • [22] Treatment options for polycystic ovary syndrome
    Badawy, Ahmed
    Elnashar, Abubaker
    INTERNATIONAL JOURNAL OF WOMENS HEALTH, 2011, 3 : 25 - 35
  • [23] A Review of Polycystic Ovary Syndrome Treatment
    Marshall, Leisa L.
    US PHARMACIST, 2024, 49 (09)
  • [24] Metformin in the treatment of polycystic ovary syndrome
    Beatriz Motta, Dra Alicia
    CURRENT PHARMACEUTICAL DESIGN, 2008, 14 (21) : 2121 - 2125
  • [25] Diagnosis and treatment of polycystic ovary syndrome
    Martinez, Ronelsys Martinez
    Salas, Raul Gonzalez
    Vela, Ariel Leonardo Alarcon
    Espin, Diana Sofia Iglesias
    MEDISUR-REVISTA DE CIENCIAS MEDICAS DE CIENFUEGOS, 2023, 21 (06): : 1338 - 1344
  • [26] Metformin for the treatment of the polycystic ovary syndrome
    Nestler, John E.
    NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (01): : 47 - 54
  • [27] Pharmacologic treatment of polycystic ovary syndrome
    Ehrmann, DA
    Rychlik, D
    SEMINARS IN REPRODUCTIVE MEDICINE, 2003, 21 (03) : 277 - 283
  • [28] Statins in the treatment of polycystic ovary syndrome
    Kodaman, Pinar H.
    Duleba, Antoni J.
    SEMINARS IN REPRODUCTIVE MEDICINE, 2008, 26 (01) : 127 - 138
  • [29] THE POLYCYSTIC OVARY SYNDROME - PATHOGENESIS AND TREATMENT
    BARNES, R
    ROSENFIELD, RL
    ANNALS OF INTERNAL MEDICINE, 1989, 110 (05) : 386 - 399
  • [30] Diagnosis and Treatment of Polycystic Ovary Syndrome
    Williams, Tracy
    Mortada, Rami
    Porter, Samuel
    AMERICAN FAMILY PHYSICIAN, 2016, 94 (02) : 106 - 113