Synergistic Activity of IDH1 Inhibitor Bay-1436032 with Azacitidine in IDH1 Mutant Acute Myeloid Leukemia

被引：0
|
作者：
Chaturvedi, Anuhar
Gupta, Charu
Goparaju, Ramya
Gabdoulline, Razif
Kaulfuss, Stefan
Gorlich, Kerstin
Schottmann, Renate
Panknin, Olaf
Wagner, Markus
Geffers, Robert
Ganser, Arnold
Thol, Felicitas
Jeffers, Michael
Haegebarth, Andrea
Heuser, Michael
机构：
来源：
BLOOD | 2017年 / 130卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1352
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
    Gruber, Emily
    So, Joan
    Lewis, Alexander C.
    Franich, Rheana
    Cole, Rachel
    Martelotto, Luciano G.
    Rogers, Amy J.
    Vidacs, Eva
    Fraser, Peter
    Stanley, Kym
    Jones, Lisa
    Trigos, Anna
    Thio, Niko
    Li, Jason
    Nicolay, Brandon
    Daigle, Scott
    Tron, Adriana E.
    Hyer, Marc L.
    Shortt, Jake
    Johnstone, Ricky W.
    Kats, Lev M.
    CELL REPORTS, 2022, 40 (07):
  • [32] BAY 1436032: A Novel Pan-mutant IDH1 Inhibitor Extends Survival of Mice with Experimental Brain Tumors
    Gokul, S.
    Rajanikant, G. K.
    CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2017, 16 (06) : 636 - 637
  • [33] Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity
    Xie, Xiaoling
    Baird, Daniel
    Bowen, Kimberly
    Capka, Vladimir
    Chen, Jinyun
    Chenail, Gregg
    Cho, YoungShin
    Dooley, Julia
    Farsidjani, Ali
    Fortin, Pascal
    Kohls, Darcy
    Kulathila, Raviraj
    Lin, Fallon
    McKay, Daniel
    Rodrigues, Lindsey
    Sage, David
    Toure, B. Barry
    van der Plas, Simon
    Wright, Kirk
    Xu, Ming
    Yin, Hong
    Levell, Julian
    Pagliarini, Raymond A.
    STRUCTURE, 2017, 25 (03) : 506 - 513
  • [34] IDH1 inhibitor-induced neutrophilic dermatosis in a patient with acute myeloid leukemia
    Dunn-Valadez, Sydney
    Bathini, Srilakshmi
    Elston, Carly
    Rangaraju, Sravanti
    Di Stasi, Antonio
    Worth, Sarah
    Morlote, Diana
    Harada, Shuko
    Vachhani, Pankit
    CANCER TREATMENT AND RESEARCH COMMUNICATIONS, 2022, 31
  • [35] Acute Myeloid Leukemia With IDH1 or IDH2 Mutation Frequency and Clinicopathologic Features
    Patel, Keyur P.
    Ravandi, Farhad
    Ma, Deqin
    Paladugu, Abhaya
    Barkoh, Bedia A.
    Medeiros, L. Jeffrey
    Luthra, Rajyalakshmi
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2011, 135 (01) : 35 - 45
  • [36] Acute myeloid leukemia with IDH1 and IDH2 mutations: 2021 treatment algorithm
    Ghayas C. Issa
    Courtney D. DiNardo
    Blood Cancer Journal, 11
  • [37] Inhibitors of mutant IDH1 and IDH2
    Pamela Feliciano
    Nature Genetics, 2013, 45 (5) : 477 - 477
  • [38] Acute myeloid leukemia with IDH1 and IDH2 mutations: 2021 treatment algorithm
    Issa, Ghayas C.
    DiNardo, Courtney D.
    BLOOD CANCER JOURNAL, 2021, 11 (06)
  • [39] Wild-type IDH1: A molecular target in IDH1 mutant cancers
    Wickenden, Julie A.
    Russell, Paul
    Smith, Amy
    Henley, Tom
    Elliott, Jane
    Gitterman, Dan
    Stockdale, Mark
    Schofield, Christine
    Torrance, Chris
    Moore, Jonathan D.
    CANCER RESEARCH, 2014, 74 (19)
  • [40] IDH1 and IDH2 mutations in pediatric acute leukemia
    A K Andersson
    D W Miller
    J A Lynch
    A S Lemoff
    Z Cai
    S B Pounds
    I Radtke
    B Yan
    J D Schuetz
    J E Rubnitz
    R C Ribeiro
    S C Raimondi
    J Zhang
    C G Mullighan
    S A Shurtleff
    B A Schulman
    J R Downing
    Leukemia, 2011, 25 : 1570 - 1577
12345