Synthesis of 5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones

被引：11
|
作者：
Gein, V. L. [1 ]
Buldakova, E. A. [1 ]
Korol, A. N. [1 ]
Veikhman, G. A. [1 ]
Dmitriev, M. V. [2 ]
机构：
[1] Perm State Pharmaceut Acad, Ul Polevaya 2, Perm 614990, Russia
[2] Perm State Natl Res Univ, Perm, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2018年 / 88卷 / 05期
关键词：
5-aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones; 2-aminoacetonitrile sulfate; tetrahydropyrrole-2,3-diones; three-component reactions;
D O I：
10.1134/S1070363218050110
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones were synthesized by a three-component reaction of methyl aroylpyruvate with a mixture of aromatic aldehyde and 2-aminoacetonitrile sulfate in glacial acetic acid in the presence of anhydrous sodium acetate.
引用
收藏
页码：908 / 911
页数：4
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