Vesicular aptasensor for the detection of thrombin

被引：11
|
作者：
Mueller, Andreas [1 ]
Koenig, Burkhard [1 ]
机构：
[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 84期
关键词：
HUMAN ALPHA-THROMBIN; COLORIMETRIC DETECTION; LABEL-FREE; APTAMER; DNA; PROTEINS; BINDING; EFFICIENCIES; DEPENDENCE; MOLECULES;
D O I：
10.1039/c4cc05221h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Self-assembled phospholipid vesicles are functionalized with thrombin-binding aptamers using a thiol-click reaction. The resulting aptasensors signal the binding of the analyte to the vesicle surface by changes of the emission properties of membrane co-embedded reporter dyes.
引用
收藏
页码：12665 / 12668
页数：4
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