The role dendritic cells play in the cytokine responses in Peyer's patches

被引：0

作者：

Sato, A ^{[1
]}

Hashiguchi, M ^{[1
]}

Hachimura, S ^{[1
]}

Kaminogawa, S ^{[1
]}

机构：

[1] Univ Tokyo, Dept Appl Biol Chem, Bunkyo Ku, Tokyo 1136857, Japan

来源：

ANIMAL CELL TECHNOLOGY : BASIC & APPLIED ASPECTS, VOL 12 | 2002年

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The role of dendritic cells (DCs) in T cell responses induced at the intestinal mucosa is unclear. Here, we demonstrate functional differences between DCs from Peyer's patch (PP) and spleen (SP), such as the ability to induce T cell differentiation. In this study, antigen presentation by PP DCs induced both Th1 and Th2 differentiation. PP DCs were found to induce increased IFN-gamma production compared to SP DCs, suggesting that DCs residing in different tissues are capable of inducing distinct immune responses.

引用

页码：213 / 217

页数：5

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