The role dendritic cells play in the cytokine responses in Peyer's patches

被引：0
|
作者：
Sato, A [1 ]
Hashiguchi, M [1 ]
Hachimura, S [1 ]
Kaminogawa, S [1 ]
机构：
[1] Univ Tokyo, Dept Appl Biol Chem, Bunkyo Ku, Tokyo 1136857, Japan
来源：
ANIMAL CELL TECHNOLOGY : BASIC & APPLIED ASPECTS, VOL 12 | 2002年
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The role of dendritic cells (DCs) in T cell responses induced at the intestinal mucosa is unclear. Here, we demonstrate functional differences between DCs from Peyer's patch (PP) and spleen (SP), such as the ability to induce T cell differentiation. In this study, antigen presentation by PP DCs induced both Th1 and Th2 differentiation. PP DCs were found to induce increased IFN-gamma production compared to SP DCs, suggesting that DCs residing in different tissues are capable of inducing distinct immune responses.
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页码：213 / 217
页数：5
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