Synthesis and resolution of 2-amino-5-aza[6]helicene

被引：3
|
作者：
Bhalodi, Esha H. [1 ]
Patel, Krupa N. [1 ]
Bedekar, Ashutosh, V [1 ]
机构：
[1] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India
来源：
TETRAHEDRON | 2022年 / 114卷
关键词：
Aza[6]helicene; CD analysis; Helical isomers; Single crystal analysis; ONE HUNDRED YEARS; STEREOSELECTIVE SYNTHESES; CHIRAL RECOGNITION; CRYSTAL-STRUCTURES; SMALL MOLECULES; PART; CARBAZOLE; HELICENE; DERIVATIVES; PHOTOCYCLIZATION;
D O I：
10.1016/j.tet.2022.132761
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of 2-amino-5-aza[6]helicene and its derivatives is reported. The diastereomeric (R)menthylcarbamate derivative of this aza[6]helicene is prepared and its isomers were physically separated by column chromatography and their optical properties were measured. Optically pure isomer (P)2-amino-5-aza[6]helicene was generated and its Boc-derivative was prepared.(c) 2022 Elsevier Ltd. All rights reserved.
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页数：7
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