The progress in quantitative evaluation of callus during distraction osteogenesis

被引:4
|
作者
Liu, Qi [1 ,2 ]
Liu, Ze [1 ,2 ]
Guo, Hongbin [1 ,2 ]
Liang, Jieyu [1 ,2 ]
Zhang, Yi [1 ,2 ]
机构
[1] Cent South Univ, Xiangya Hosp, Dept Orthopaed, Changsha 410008, Hunan, Peoples R China
[2] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
Distraction osteogenesis; Quantitative evaluation; Callus; Imaging; Biomechanical evaluation; Biochemical markers; X-RAY ABSORPTIOMETRY; FRACTURE RISK-ASSESSMENT; LOAD-BEARING CAPACITY; BONE-MINERAL DENSITY; IN-VIVO ASSESSMENT; COMPUTED-TOMOGRAPHY; MECHANICAL CHARACTERIZATION; STIFFNESS MEASUREMENTS; IMAGING TECHNIQUES; AXIAL STIFFNESS;
D O I
10.1186/s12891-022-05458-8
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The manual monitoring of callus with digital radiography (X-ray) is the primary bone healing evaluation, assessing the number of bridged callus formations. However, this method is subjective and nonquantitative. Recently, several quantitative monitoring methods, which could assess the recovery of the structure and biomechanical properties of the callus at different stages and the process of bone healing, have been extensively investigated. These methods could reflect the bone mineral content (BMC), bone mineral density (BMD), stiffness, callus and bone metabolism at the site of bone lengthening. In this review, we comprehensively summarized the latest techniques for evaluating bone healing during distraction osteogenesis (DO): 1) digital radiography; 2) dual-energy X-ray scanning; 3) ultrasound; 4) quantitative computed tomography; 5) biomechanical evaluation; and 6) biochemical markers. This evidence will provide novel and significant information for evaluating bone healing during DO in the future.
引用
收藏
页数:12
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