The Distraction Osteogenesis Callus: a Review of the Literature

被引：1
|
作者：
Rozis, Meletis [1 ]
Polyzois, Vasileios [1 ]
Pneumaticos, Spyros [1 ]
机构：
[1] Univ Athens, KAT Hosp, Orthopaed Dept 3, Athens, Greece
来源：
CLINICAL REVIEWS IN BONE AND MINERAL METABOLISM | 2021年 / 19卷 / 1-4期
关键词：
Distraction osteogenesis; Callus; External fixation; BONE MORPHOGENETIC PROTEIN-2; MESENCHYMAL STEM-CELLS; INTENSITY PULSED ULTRASOUND; GROWTH-HORMONE; MANDIBULAR DISTRACTION; MECHANICAL CHARACTERIZATION; RABBIT MODEL; MOUSE MODEL; EXPRESSION; INCREASES;
D O I：
10.1007/s12018-021-09282-x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The distraction osteogenesis has been an integrated treatment approach in significant bone deficiencies resulting from debridement or high-energy trauma. Nevertheless, it usually demands a prolonged treatment period attributed to the more profound distraction osteogenesis callus physiology. This distraction callus is a tissue not naturally present in mammals and results after surgical intervention. Despite sharing quite similar molecular and biomechanical mechanisms to the fracture-healing callus, it recruits unique physiological pathways. This review presents the deep physiology of the distraction osteogenesis callus, the familiar pathways with the fracture healing callus, and current maturation's acceleration tactic concepts.
引用
收藏
页码：24 / 35
页数：12
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