CCR2 DEFICIENCY IMPAIRS MACROPHAGE INFILTRATION AND IMPROVES COGNITIVE FUNCTION AFTER TRAUMATIC BRAIN INJURY

被引:0
|
作者
Hsieh, C. L. [1 ,2 ]
Niemi, E. C. [1 ,2 ]
Wang, S. H. [1 ]
Lee, C. [1 ,2 ]
Bingham, D. [1 ,2 ]
Zhang, J. [1 ,2 ]
Charo, I [1 ]
Huang, E. J. [1 ,2 ]
Liu, J. [1 ,2 ]
Nakamura, M. C. [1 ,2 ]
机构
[1] Univ Calif San Francisco, San Francisco, CA 94143 USA
[2] San Francisco VA Med Ctr, San Francisco, CA USA
关键词
behavior studies; CCR2; flow cytometry; inflammation; macrophage; traumatic brain injury;
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
D1-31
引用
收藏
页码:A111 / A111
页数:1
相关论文
共 50 条
  • [31] Metformin reduces neuroinflammation and improves cognitive functions after traumatic brain injury
    DiBona, Victoria L.
    Shah, Mihir K.
    Krause, Kayla J.
    Zhu, Wenxin
    Voglewede, Mikayla M.
    Smith, Dana M.
    Crockett, David P.
    Zhang, Huaye
    NEUROSCIENCE RESEARCH, 2021, 172 : 99 - 109
  • [32] Donepezil improves cognitive recovery after traumatic brain injury in mongolian gerbils
    Li, Shihong
    Kuroiwa, Toshihiko
    Ishibashi, Satoru
    Sun, Liyuan
    Endo, Shu
    Ohno, Kikuo
    JOURNAL OF NEUROTRAUMA, 2006, 23 (06) : 998 - 998
  • [33] Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury
    Zhang, Yanlu
    Chopp, Michael
    Meng, Yuling
    Zhang, Zheng Gang
    Doppler, Edith
    Winter, Stefan
    Schallert, Timothy
    Mahmood, Asim
    Xiong, Ye
    JOURNAL OF NEUROSURGERY, 2015, 122 (04) : 843 - 855
  • [34] Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer's disease
    El Khoury, Joseph
    Toft, Michelle
    Hickman, Suzanne
    Geula, Changiz
    Means, Terry
    Luster, Andrew
    CLINICAL IMMUNOLOGY, 2007, 123 : S138 - S138
  • [35] Effect of Fluoxetine on Cognitive Function after Traumatic Brain Injury in Rats
    Ailibo, Jiangchao
    Guoyanhua, Liuchuan
    Tao, Wanghai
    LATIN AMERICAN JOURNAL OF PHARMACY, 2021, 40 (11): : 2579 - 2584
  • [36] Treatment with low-dose methamphetamine improves behavioral and cognitive function after severe traumatic brain injury
    Rau, Thomas F.
    Kothiwal, Aakriti S.
    Rova, Annela R.
    Brooks, Diane M.
    Poulsen, David J.
    JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2012, 73 : S165 - S172
  • [37] Inhibition of Src Family Kinases Protects Hippocampal Neurons and Improves Cognitive Function after Traumatic Brain Injury
    Liu, Da Zhi
    Sharp, Frank R.
    Van, Ken C.
    Ander, Bradley P.
    Ghiasvand, Rahil
    Zhan, Xinhua
    Stamova, Boryana
    Jickling, Glen C.
    Lyeth, Bruce G.
    JOURNAL OF NEUROTRAUMA, 2014, 31 (14) : 1268 - 1276
  • [38] Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury
    Zhu, J
    Hamm, RJ
    Reeves, TM
    Povlishock, JT
    Phillips, LL
    EXPERIMENTAL NEUROLOGY, 2000, 166 (01) : 136 - 152
  • [39] Monocyte/macrophage chemokine receptor CCR2 mediates diabetic renal injury
    Awad, Alaa S.
    Kinsey, Gilbert R.
    Khutsishvili, Konstantine
    Gao, Ting
    Bolton, W. Kline
    Okusa, Mark D.
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2011, 301 (06) : F1358 - F1366
  • [40] The CCR2 Antagonist CCX140 Improves Renal Function and Hyperglycemia in Diabetic Mice Expressing Human CCR2
    Powers, Jay P.
    Sullivan, Timothy J.
    Miao, Zhenhua
    Zhao, Niky
    Berahovich, Robert D.
    Ertl, Linda
    Walters, Matthew J.
    Dang, Ton
    Miao, Shichang
    Jaen, Juan C.
    Schall, Thomas J.
    DIABETES, 2013, 62 : A27 - A27