Four new eremophilanlides (1-4) together with a known sesquiterpene were isolated from the roots and rhizomes of Ligularia hodgsonii. The structures of these new compounds were established as 6 beta-(2'-methylbutanoyloxy)-10 beta-acetoxy-3 beta,8 beta-dihydroxyeremophil-7(11)-en-8,12-olide (1), 60,10 beta-dihydroxyeremophil-7(11)-en-8 alpha,12-olide (2), 3 beta-acetoxy-6,9-dien-8-oxoeremophil-12-nor-11 -ketone (3), and 3 beta-acetoxy-6 alpha,8 alpha-dihydroxyeremophil-7(11),9-dien-8,12-olide (4) by means of mass, IR and NMR spectroscopy.